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General Approach to Patients with Autonomic Disorders: “What Is the Autonomic Disease?” – A Basic Tutorial to Autonomic Physiology and Pathophysiology

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Abstract

Disorders of the autonomic nervous system (ANS) are often a severe burden to the quality of life of our patients (e.g., orthostatic intolerance, sweating disorders, sexual dysfunction). In some cases, they may be harmful (syncope with falls, heat intolerance, urinary retention) or even life threatening (sudden cardiac death, sympathetic storm, heat shock). Diagnosis of ANS disorders is still underrepresented, despite their common occurrence in clinical practice. This may be attributed at least in part to a lack of awareness and attention to symptoms of ANS dysfunction. Information on the ANS is rare in many neurological textbooks and often missing during education. This booklet shall help to recognize the presence and distribution of autonomic dysfunctions and provide tips for further management. The clinical investigations of autonomic functions presented here refer to the office, bedside, or prelaboratory evaluation. It cannot and shall not replace any textbook in this growing, neurological field.

H. Lahrmann, W. Struhal together with all co-authors.

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References

  1. Lahrmann H, Magnifico F, Haensch CA, Cortelli P (2005) Autonomic nervous system laboratories: a European survey. Eur J Neurol 12:375–379

    Article  CAS  PubMed  Google Scholar 

  2. Winker R, Prager W, Haider A, Salameh B, Rudiger HW (2005) Schellong test in orthostatic dysregulation: a comparison with tilt-table testing. Wien Klin Wochenschr 117:36–41

    Article  PubMed  Google Scholar 

  3. Ewing DJ, Clarke BF (1982) Diagnosis and management of diabetic autonomic neuropathy. Br Med J 285:916–918

    Google Scholar 

  4. Low PA, Sandroni P, Benarroch EE (2008) Clinical autonomic disorders: classification and clinical evaluation. In: Low PA, Benarroch EE (eds) Clinical autonomic disorders, 3rd edn. Wolters Kluwer, Philadelphia, pp 1–17

    Google Scholar 

  5. Benarroch EE (1993) The central autonomic network: functional organization dysfunction, and perspective. Mayo Clin Proc 68(10):988–1001

    Article  CAS  PubMed  Google Scholar 

  6. Struhal W, Hoedl S, Lahrmann H, Toeglhofer E, Gruber F, Vosko M, Ransmayr G (2011) Reliability of the noninvasive sequence methods to estimate baroreflex function using the paradigm of brain death. Auton Neurosci 161(1–2):43–45

    Article  CAS  PubMed  Google Scholar 

  7. Lahrmann H et al (2006) EFNS guidelines on the diagnosis and management of orthostatic hypotension. Eur J Neurol 13:930–936

    Article  CAS  PubMed  Google Scholar 

  8. Ward SM, Sanders KM (2006) Involvement of intramuscular interstitial cells of Cajal in neuroeffector transmission in the gastrointestinal tract. J Physiol 576(Pt 3):675–682

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Olsson C, Holmgren S (2001) The control of gut motility. Comp Biochem Physiol 128:481–503

    Article  CAS  Google Scholar 

  10. Altaf MA, Sood MR (2008) The nervous system and gastrointestinal function. Developmental disabilities research reviews 14:87–95

    Google Scholar 

  11. Drake MJ, Fowler CJ, Griffiths D, Mayer E, Paton JF, Birder L. Neural control of the lower urinary and gastrointestinal tracts: supraspinal CNS mechanisms. Neurourol Urodyn. 2010;29(1):119–27.

    Google Scholar 

  12. Grimaldi D, Silvani A, Benarroch EE, Cortelli P (2014) Orexin/hypocretin system and autonomic control: new insights and clinical correlations. Neurology 82:271–278

    Article  PubMed  Google Scholar 

  13. American Academy of Sleep Medicine (AASM) (2014) The international classification of sleep disorders, 3rd edn. American Academy of Sleep Medicine, Darien, IL, 2014.

    Google Scholar 

  14. Boudreau P, Yeh WH, Dumont GA, Boivin DB (2013) Circadian variation of heart rate variability across sleep stages. Sleep 36(12):1919–1928. doi:10.5665/sleep.3230

  15. Task Force of the American Academy of Sleep Medicine (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5(3):263–276

    Google Scholar 

  16. Tobaldini E, Nobili L, Strada S, Casali KR, Braghiroli A, Montano N (2013) Heart rate variability in normal and pathological sleep. Front Physiol 4:294. doi:10.3389/fphys.2013.00294

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Correspondence to Heinz Lahrmann .

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Lahrmann, H., Struhal, W. (2017). General Approach to Patients with Autonomic Disorders: “What Is the Autonomic Disease?” – A Basic Tutorial to Autonomic Physiology and Pathophysiology. In: Struhal, W., Lahrmann, H., Fanciulli, A., Wenning, G. (eds) Bedside Approach to Autonomic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-05143-7_1

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  • DOI: https://doi.org/10.1007/978-3-319-05143-7_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-05142-0

  • Online ISBN: 978-3-319-05143-7

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