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Women's Reproductive Mental Health Across the Lifespan pp 49–72Cite as

Menstruation and Premenstrual Dysphoric Disorder: Its Impact on Mood

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Abstract

In the premenstruum, women may experience physical or affective symptoms such as fatigue, irritability, or bloating. Such symptoms occur on a continuum, with approximately 3–8 % of women experiencing symptoms severe enough to impact function in daily activities. This severe cluster of symptoms is classified as Premenstrual Dysphoric Disorder (PMDD). Researchers continue to unravel the biopsychosocial contributors to premenstrual symptoms, including stress and hormonal changes. Women with premenstrual symptoms likely have altered central nervous system sensitivity to normal hormonal fluctuations. In particular, altered GABAergic response to neurosteroid metabolites may be key in the etiology of PMDD. This chapter includes a brief overview of the menstrual cycle, PMDD diagnosis and pathophysiology, and treatment approaches.

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References

  • ACOG. (2001). ACOG Practice bulletin: Premenstrual syndrome. Clinical management guidelines for obstetrician-gynecologists. International Journal of Gynecology & Obstetrics, 73, 183–191.

    Google Scholar 

  • Allen, S. S., McBride, C. M., & Pirie, P. L. (1991). The shortened premenstrual assessment form. The Journal of Reproductive Medicine, 36(11), 769–772.

    Google Scholar 

  • Amin, Z., Canli, T., & Epperson, C. N. (2005). Effect of estrogen-serotonin interactions on mood and cognition. Behavioral and Cognitive Neuroscience Reviews, 4(1), 43–58. doi:10.1177/1534582305277152.

    Google Scholar 

  • Angst, J., Sellaro, R., Merikangas, K. R., & Endicott, J. (2001). The epidemiology of perimenstrual psychological symptoms. Acta Psychiatrica Scandinavica, 104(2), 110–116.

    Google Scholar 

  • APA. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: APA.

    Google Scholar 

  • APA (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: APA

    Google Scholar 

  • Baller, E. B., Wei, S. M., Kohn, P. D., Rubinow, D. R., Alarcón, G., Schmidt, P. J., & Berman, K. F. (2013). Abnormalities of dorsolateral prefrontal function in women with premenstrual dysphoric disorder: A multimodal neuroimaging study. The American Journal of Psychiatry, 170(3), 305–314. doi:10.1176/appi.ajp.2012.12030385

  • Bancroft, J., & Rennie, D. (1993). The impact of oral contraceptives on the experience of perimenstrual mood, clumsiness, food craving and other symptoms. Journal of Psychosomatic Research, 37(2), 195–202.

    Google Scholar 

  • Bannbers, E., Kask, K., Wikström, J., Risbrough, V., & Poromaa, I. S. (2011). Patients with premenstrual dysphoric disorder have increased startle modulation during anticipation in the late luteal phase period in comparison to control subjects. Psychoneuroendocrinology, 36(8), 1184–1192. doi:10.1016/j.psyneuen.2011.02.011.

    Google Scholar 

  • Bazán, A. C. B., Montenegro, M. A., Cendes, F., Min, L. L., & Guerreiro, C. A. M. (2005). Menstrual cycle worsening of epileptic seizures in women with symptomatic focal epilepsy. Arquivos de Neuro-Psiquiatria, 63(3), 751–756. http://dx.doi.org/10.1590/S0004-282X2005000500006.

    Google Scholar 

  • Berman, S. M., London, E. D., Morgan, M., & Rapkin, A. J. (2013). Elevated gray matter volume of the emotional cerebellum in women with premenstrual dysphoric disorder. Journal of Affective Disorders, 146(2), 266–271. doi:10.1016/j.jad.2012.06.038.

    Google Scholar 

  • Bertrand, P. P., Paranavitane, U. T., Chavez, C., Gogos, A., Jones, M., & van den Buuse, M. (2005). The effect of low estrogen state on serotonin transporter function in mouse hippocampus: A behavioral and electrochemical study. Brain Research, 1064(1–2), 10–20. doi:10.1016/j.brainres.2005.10.018.

    Google Scholar 

  • Bloch, M., Rotenberg, N., Koren, D., & Klein, E. (2006). Risk factors for early postpartum depressive symptoms. General Hospital Psychiatry, 28(1), 3–8. doi:10.1016/j.genhosppsych.2005.08.006.

    Google Scholar 

  • Borenstein, J., Chiou, C. F., Dean, B., Wong, J., & Wade, S. (2005). Estimating direct and indirect costs of premenstrual syndrome. Journal of Occupational and Environmental Medicine, 47(1), 26–33.

    Google Scholar 

  • Borenstein, J. E., Dean, B. B., Endicott, J., Wong, J., Brown, C., Dickerson, V., & Yonkers, K. A. (2003). Health and economic impact of the premenstrual syndrome. The Journal of Reproductive Medicine, 48(7), 515–524.

    Google Scholar 

  • Brown, M. A., & Lewis, L. L. (1993). Cycle-phase changes in perceived stress in women with varying levels of premenstrual symptomatology. Research in Nursing & Health, 16(6), 423–429.

    Google Scholar 

  • Brown, J., O’ Brien, P. M. S., Marjoribanks, J., & Wyatt, K. (2009). Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database of Systematic Reviews (Online), (2), CD001396. doi:10.1002/14651858.CD001396.pub2

  • Busse, J. W., Montori, V. M., Krasnik, C., Patelis-Siotis, I., & Guyatt, G. H. (2009). Psychological intervention for premenstrual syndrome: A meta-analysis of randomized controlled trials. Psychotherapy and Psychosomatics, 78(1), 6–15. doi:10.1159/000162296.

    Google Scholar 

  • Childs, E., Dlugos, A., & De Wit, H. (2010). Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology, 47(3), 550–559. doi:10.1111/j.1469-8986.2009.00961.x.

    Google Scholar 

  • Chuong, C. J., & Burgos, D. M. (1995). Medical history in women with premenstrual syndrome. Journal of Psychosomatic Obstetrics and Gynaecology, 16(1), 21–27.

    Google Scholar 

  • Cohen, L. S., Soares, C. N., Otto, M. W., Sweeney, B. H., Liberman, R. F., & Harlow, B. L. (2002). Prevalence and predictors of premenstrual dysphoric disorder (PMDD) in older premenopausal women. The Harvard Study of Moods and Cycles. Journal of Affective Disorders, 70(2), 125–132.

    Google Scholar 

  • Cunningham, J., Yonkers, K. A., O’Brien, S., & Eriksson, E. (2009). Update on research and treatment of premenstrual dysphoric disorder. Harvard Review of Psychiatry, 17(2), 120–137. doi:10.1080/10673220902891836.

    Google Scholar 

  • Dambhare, D. G., Wagh, S. V., & Dudhe, J. Y. (2012). Age at menarche and menstrual cycle pattern among school adolescent girls in Central India. Global Journal of Health Science, 4(1), 105–111.

    Google Scholar 

  • de Wit, H., & Rukstalis, M. (1997). Acute effects of triazolam in women: Relationships with progesterone, estradiol, and allopregnanolone. Psychopharmacology, 130(1), 69–78.

    Google Scholar 

  • Dennerstein, L., Lehert, P., Burger, H., & Dudley, E. (1999). Mood and the menopausal transition. The Journal of Nervous and Mental Disease, 187(11), 685–691.

    Google Scholar 

  • Dhingra, V., Magnay, J. L., O’Brien, P. M. S., Chapman, G., Fryer, A. A., & Ismail, K. M. K. (2007). Serotonin receptor 1A C(-1019)G polymorphism associated with premenstrual dysphoric disorder. Obstetrics and Gynecology, 110(4), 788–792. doi:10.1097/01.AOG.0000284448.73490.ac.

    Google Scholar 

  • Endicott, J., Nee, J., & Harrison, W. (2006). Daily record of severity of problems (DRSP): Reliability and validity. Archives of Women's Mental Health, 9(1), 41–49. doi:10.1007/s00737-005-0103-y.

    Google Scholar 

  • Epperson, C. N., Haga, K., Mason, G. F., Sellers, E., Gueorguieva, R., Zhang, W., … Krystal, J. H. (2002). Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: A proton magnetic resonance spectroscopy study. Archives of General Psychiatry, 59(9), 851–858.

    Google Scholar 

  • Epperson, C., Pittman, B., Czarkowski, K. A., Stiklus, S., Krystal, J. H., & Grillon, C. (2007). Luteal-phase accentuation of acoustic startle response in women with premenstrual dysphoric disorder. Neuropsychopharmacology, 32(10), 2190–2198. doi:10.1038/sj.npp.1301351.

    Google Scholar 

  • Epperson, C., Steiner, M., Hartlage, S. A., Eriksson, E., Schmidt, P. J., Jones, I., & Yonkers, K. A. (2012). Premenstrual dysphoric disorder: Evidence for a new category for DSM-5. The American Journal of Psychiatry, 169(5), 465–475.

    Google Scholar 

  • Evans, S. M., Haney, M., Levin, F. R., Foltin, R. W., & Fischman, M. W. (1998). Mood and performance changes in women with premenstrual dysphoric disorder: Acute effects of alprazolam. Neuropsychopharmacology, 19(6), 499–516. doi:10.1016/S0893-133X(98)00064-5.

    Google Scholar 

  • Facchinetti, F., Fioroni, L., Martignoni, E., Sances, G., Costa, A., & Genazzani, A. R. (1994). Changes of opioid modulation of the hypothalamo-pituitary-adrenal axis in patients with severe premenstrual syndrome. Psychosomatic Medicine, 56(5), 418–422.

    Google Scholar 

  • Feuerstein, M., & Shaw, W. S. (2002). Measurement properties of the calendar of premenstrual experience in patients with premenstrual syndrome. The Journal of Reproductive Medicine, 47(4), 279–289.

    Google Scholar 

  • Fink, G., Sumner, B. E., McQueen, J. K., Wilson, H., & Rosie, R. (1998). Sex steroid control of mood, mental state and memory. Clinical and Experimental Pharmacology & Physiology, 25(10), 764–775.

    Google Scholar 

  • Ford, O., Lethaby, A., Roberts, H., & Mol, B. W. J. (2012). Progesterone for premenstrual syndrome. Cochrane Database of Systematic Reviews (Online), 3, CD003415. doi:10.1002/14651858.CD003415.pub4.

    Google Scholar 

  • Freeman, E. W. (2004). Luteal phase administration of agents for the treatment of premenstrual dysphoric disorder. CNS Drugs, 18(7), 453–468.

    Google Scholar 

  • Freeman, E. W., Halberstadt, S. M., Rickels, K., Legler, J. M., Lin, H., & Sammel, M. D. (2011). Core symptoms that discriminate premenstrual syndrome. Journal of Women's Health (2002), 20(1), 29–35. doi:10.1089/jwh.2010.2161.

    Google Scholar 

  • Freeman, E. W, Halbreich, U., Grubb, G. S., Rapkin, A. J., Skouby, S. O., Smith, L., … Constantine, G. D. (2012). An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome. Contraception, 85(5), 437–445. doi:10.1016/j.contraception.2011.09.010

  • Freeman, E. W., Rickels, K., Schweizer, E., & Ting, T. (1995). Relationships between age and symptom severity among women seeking medical treatment for premenstrual symptoms. Psychological Medicine, 25(2), 309–315.

    Google Scholar 

  • Freeman, E. W., Rickels, K., Sondheimer, S. J., & Polansky, M. (1995). A double-blind trial of oral progesterone, alprazolam, and placebo in treatment of severe premenstrual syndrome. JAMA: The Journal of the American Medical Association, 274(1), 51–57.

    Google Scholar 

  • Freeman, E. W., Sammel, M. D., Liu, L., Gracia, C. R., Nelson, D. B., & Hollander, L. (2004). Hormones and menopausal status as predictors of depression in women in transition to menopause. Archives of General Psychiatry, 61(1), 62–70. doi:10.1001/archpsyc.61.1.62.

    Google Scholar 

  • Freeman, E. W., Sammel, M. D., Rinaudo, P. J., & Sheng, L. (2004). Premenstrual syndrome as a predictor of menopausal symptoms. Obstetrics and Gynecology, 103(5 Pt 1), 960–966. doi:10.1097/01.AOG.0000124804.81095.7f.

    Google Scholar 

  • Freeman, E. W., Sondheimer, S. J., Sammel, M. D., Ferdousi, T., & Lin, H. (2005). A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder. The Journal of Clinical Psychiatry, 66(6), 769–773.

    Google Scholar 

  • Gallo, M. A., & Smith, S. S. (1993). Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: A possible rat model of PMS anxiety. Pharmacology, Biochemistry, and Behavior, 46(4), 897–904.

    Google Scholar 

  • Gaskins, A. J., Wilchesky, M., Mumford, S. L., Whitcomb, B. W., Browne, R. W., Wactawski-Wende, J., … Schisterman, E. F. (2012). Endogenous reproductive hormones and C-reactive protein across the menstrual cycle: The BioCycle Study. American Journal of Epidemiology, 175(5), 423–431. doi:10.1093/aje/kwr343

  • Gingnell, M., Comasco, E., Oreland, L., Fredrikson, M., & Sundström-Poromaa, I. (2010). Neuroticism-related personality traits are related to symptom severity in patients with premenstrual dysphoric disorder and to the serotonin transporter gene-linked polymorphism 5-HTTPLPR. Archives of Women's Mental Health, 13(5), 417–423. doi:10.1007/s00737-010-0164-4.

    Google Scholar 

  • Girdler, S. S., Leserman, J., Bunevicius, R., Klatzkin, R., Pedersen, C. A., & Light, K. C. (2007). Persistent alterations in biological profiles in women with abuse histories: Influence of premenstrual dysphoric disorder. Health Psychology, 26(2), 201–213. doi:10.1037/0278-6133.26.2.201.

    Google Scholar 

  • Girdler, S. S., Pedersen, C. A., Straneva, P. A., Leserman, J., Stanwyck, C. L., Benjamin, S., & Light, K. C. (1998). Dysregulation of cardiovascular and neuroendocrine responses to stress in premenstrual dysphoric disorder. Psychiatry Research, 81(2), 163–178. doi:10.1016/S0165-1781(98)00074-2

  • Girdler, S. S., Straneva, P. A., Light, K. C., Pedersen, C. A., & Morrow, A. L. (2001). Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biological Psychiatry, 49(9), 788–797.

    Google Scholar 

  • Golding, J. M., Taylor, D. L., Menard, L., & King, M. J. (2000). Prevalence of sexual abuse history in a sample of women seeking treatment for premenstrual syndrome. Journal of Psychosomatic Obstetrics and Gynaecology, 21(2), 69–80.

    Google Scholar 

  • Graham, C. A., & Sherwin, B. B. (1992). A prospective treatment study of premenstrual symptoms using a triphasic oral contraceptive. Journal of Psychosomatic Research, 36(3), 257–266.

    Google Scholar 

  • Griffin, L. D., & Mellon, S. H. (1999). Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proceedings of the National Academy of Sciences of the United States of America, 96(23), 13512–13517.

    Google Scholar 

  • Gulinello, M., Gong, Q. H., & Smith, S. S. (2002). Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology—a comparison with female rats. Neuropharmacology, 43(4), 701–714.

    Google Scholar 

  • Gulinello, M., Orman, R., & Smith, S. S. (2003). Sex differences in anxiety, sensorimotor gating and expression of the alpha4 subunit of the GABAA receptor in the amygdala after progesterone withdrawal. The European Journal of Neuroscience, 17(3), 641–648.

    Google Scholar 

  • Haggerty, C. L., Ness, R. B., Kelsey, S., & Waterer, G. W. (2003). The impact of estrogen and progesterone on asthma. Annals of Allergy, Asthma & Immunology, 90(3), 284–291; quiz 291–293, 347. doi:10.1016/S1081-1206(10)61794-2

  • Halbreich, U. (2004). The diagnosis of premenstrual syndromes and premenstrual dysphoric disorder—clinical procedures and research perspectives. Gynecological Endocrinology, 19(6), 320–334.

    Google Scholar 

  • Halbreich, U. (2008). Selective serotonin reuptake inhibitors and initial oral contraceptives for the treatment of PMDD: Effective but not enough. CNS Spectrums, 13(7), 566–572.

    Google Scholar 

  • Halbreich, U., Borenstein, J., Pearlstein, T., & Kahn, L. S. (2003). The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD). Psychoneuroendocrinology, 28(Suppl 3), 1–23.

    Google Scholar 

  • Haley, C. L., Sung, S. C., Rush, A. J., Trivedi, M. H., Wisniewski, S. R., Luther, J. F., & Kornstein, S. G. (2013). The clinical relevance of self-reported premenstrual worsening of depressive symptoms in the management of depressed outpatients: a STAR*D report. Journal of Women’s Health (2002), 22(3), 219–229. doi:10.1089/jwh.2011.3186

  • Hamaideh, S. H., Al-Ashram, S. A., & Al-Modallal, H. (2013). Premenstrual syndrome and premenstrual dysphoric disorder among Jordanian women. Journal of Psychiatric and Mental Health Nursing. doi:10.1111/jpm.12047.

    Google Scholar 

  • Hartlage, S. A., Brandenburg, D. L., & Kravitz, H. M. (2004). Premenstrual exacerbation of depressive disorders in a community-based sample in the United States. Psychosomatic Medicine, 66(5), 698–706. doi:10.1097/01.psy.0000138131.92408.b9.

    Google Scholar 

  • Hartlage, S. A., Freels, S., Gotman, N., & Yonkers, K. (2012). Criteria for premenstrual dysphoric disorder: Secondary analyses of relevant data sets. Archives of General Psychiatry, 69(3), 300–305. doi:10.1001/archgenpsychiatry.2011.1368.

    Google Scholar 

  • Heinemann, L. A. J., Minh, T. D., Heinemann, K., Lindemann, M., & Filonenko, A. (2012). Intercountry assessment of the impact of severe premenstrual disorders on work and daily activities. Health Care for Women International, 33(2), 109–124. doi:10.1080/07399332.2011.610530.

    Google Scholar 

  • Hong, J., Park, S., Wang, H.-R., Chang, S., Sohn, J., Jeon, H., … Cho, M. (n.d.). Prevalence, correlates, comorbidities, and suicidal tendencies of premenstrual dysphoric disorder in a nationwide sample of Korean women. Social Psychiatry and Psychiatric Epidemiology, 1–9. doi:10.1007/s00127-012-0509-6

  • Hsiao, M.-C., Hsiao, C.-C., & Liu, C.-Y. (2004). Premenstrual symptoms and premenstrual exacerbation in patients with psychiatric disorders. Psychiatry and Clinical Neurosciences, 58(2), 186–190.

    Google Scholar 

  • Hsiao, C.-C., Liu, C.-Y., & Hsiao, M.-C. (2004). No correlation of depression and anxiety to plasma estrogen and progesterone levels in patients with premenstrual dysphoric disorder. Psychiatry and Clinical Neurosciences, 58(6), 593–599. doi:10.1111/j.1440-1819.2004.01308.x.

    Google Scholar 

  • Huo, L., Straub, R. E., Roca, C., Schmidt, P. J., Shi, K., Vakkalanka, R., … Rubinow, D. R. (2007). Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene. Biological Psychiatry, 62(8), 925–933. doi:10.1016/j.biopsych.2006.12.019

  • Jahanfar, S., Lye, M.-S., & Krishnarajah, I. S. (2011). The heritability of premenstrual syndrome. Twin Research and Human Genetics, 14(5), 433–436. doi:10.1375/twin.14.5.433.

    Google Scholar 

  • Jane, Z.-Y., Chang, C.-C., Lin, H.-K., Liu, Y.-C., & Chen, W.-L. (2011). The association between the exacerbation of irritable bowel syndrome and menstrual symptoms in young Taiwanese women. Gastroenterology Nursing, 34(4), 277–286. doi:10.1097/SGA.0b013e3182248708.

    Google Scholar 

  • Jeong, H.-G., Ham, B.-J., Yeo, H. B., Jung, I.-K., & Joe, S.-H. (2012). Gray matter abnormalities in patients with premenstrual dysphoric disorder: An optimized voxel-based morphometry. Journal of Affective Disorders, 140(3), 260–267. doi:10.1016/j.jad.2012.02.010.

    Google Scholar 

  • Kane, S. V., Sable, K., & Hanauer, S. B. (1998). The menstrual cycle and its effect on inflammatory bowel disease and irritable bowel syndrome: A prevalence study. The American Journal of Gastroenterology, 93(10), 1867–1872. doi:10.1111/j.1572-0241.1998.540_i.x.

    Google Scholar 

  • Kask, K., Gulinello, M., Bäckström, T., Geyer, M. A., & Sundström-Poromaa, I. (2008). Patients with premenstrual dysphoric disorder have increased startle response across both cycle phases and lower levels of prepulse inhibition during the late luteal phase of the menstrual cycle. Neuropsychopharmacology, 33(9), 2283–2290. doi:10.1038/sj.npp.1301599.

    Google Scholar 

  • Kendler, K. S., Karkowski, L. M., Corey, L. A., & Neale, M. C. (1998). Longitudinal population-based twin study of retrospectively reported premenstrual symptoms and lifetime major depression. The American Journal of Psychiatry, 155(9), 1234–1240.

    Google Scholar 

  • Kirschbaum, C., Kudielka, B. M., Gaab, J., Schommer, N. C., & Hellhammer, D. H. (1999). Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosomatic Medicine, 61(2), 154–162.

    Google Scholar 

  • Kleinstäuber, M., Witthöft, M., & Hiller, W. (2012). Cognitive-behavioral and pharmacological interventions for premenstrual syndrome or premenstrual dysphoric disorder: A meta-analysis. Journal of Clinical Psychology in Medical Settings, 19(3), 308–319. doi:10.1007/s10880-012-9299-y.

    Google Scholar 

  • Koci, A., & Strickland, O. (2007). Relationship of adolescent physical and sexual abuse to perimenstrual symptoms (PMS) in adulthood. Issues in Mental Health Nursing, 28(1), 75–87. doi:10.1080/01612840600996281.

    Google Scholar 

  • Kornstein, S. G., Harvey, A. T., Rush, A. J., Wisniewski, S. R., Trivedi, M. H., Svikis, D. S., … Harley, R. (2005). Self-reported premenstrual exacerbation of depressive symptoms in patients seeking treatment for major depression. Psychological Medicine, 35(5), 683–692.

    Google Scholar 

  • Kornstein, S. G., Pearlstein, T. B., Fayyad, R., Farfel, G. M., & Gillespie, J. A. (2006). Low-dose sertraline in the treatment of moderate-to-severe premenstrual syndrome: Efficacy of 3 dosing strategies. The Journal of Clinical Psychiatry, 67(10), 1624–1632.

    Google Scholar 

  • Kuczmierczyk, A. R., Labrum, A. H., & Johnson, C. C. (1992). Perception of family and work environments in women with premenstrual syndrome. Journal of Psychosomatic Research, 36(8), 787–795.

    Google Scholar 

  • Landén, M., & Eriksson, E. (2003). How does premenstrual dysphoric disorder relate to depression and anxiety disorders? Depression and Anxiety, 17(3), 122–129. doi:10.1002/da.10089.

    Google Scholar 

  • Landén, M., Nissbrandt, H., Allgulander, C., Sörvik, K., Ysander, C., & Eriksson, E. (2007). Placebo-controlled trial comparing intermittent and continuous paroxetine in premenstrual dysphoric disorder. Neuropsychopharmacology, 32(1), 153–161. doi:10.1038/sj.npp.1301216.

    Google Scholar 

  • Landén, M., & Thase, M. E. (2006). A model to explain the therapeutic effects of serotonin reuptake inhibitors: The role of 5-HT2 receptors. Psychopharmacology Bulletin, 39(1), 147–166.

    Google Scholar 

  • Lee, E. E., Nieman, L. K., Martinez, P. E., Harsh, V. L., Rubinow, D. R., & Schmidt, P. J. (2012). ACTH and cortisol response to Dex/CRH testing in women with and without premenstrual dysphoria during GnRH agonist-induced hypogonadism and ovarian steroid replacement. The Journal of Clinical Endocrinology and Metabolism, 97(6), 1887–1896. doi:10.1210/jc.2011-3451.

    Google Scholar 

  • Li, Y., Pehrson, A. L., Budac, D. P., Sánchez, C., & Gulinello, M. (2012). A rodent model of premenstrual dysphoria: Progesterone withdrawal induces depression-like behavior that is differentially sensitive to classes of antidepressants. Behavioural Brain Research, 234(2), 238–247. doi:10.1016/j.bbr.2012.06.034.

    Google Scholar 

  • Lokuge, S., Frey, B. N., Foster, J. A., Soares, C. N., & Steiner, M. (2010). The rapid effects of estrogen: A mini-review. Behavioural Pharmacology, 21(5–6), 465–472. doi:10.1097/FBP.0b013e32833da5c3.

    Google Scholar 

  • Lopez, L. M., Kaptein, A. A., & Helmerhorst, F. M. (2012). Oral contraceptives containing drospirenone for premenstrual syndrome. Cochrane Database of Systematic Reviews (Online), 2, CD006586. doi:10.1002/14651858.CD006586.pub4.

    Google Scholar 

  • Lurie, S., & Borenstein, R. (1990). The premenstrual syndrome. Obstetrical & Gynecological Survey, 45(4), 220–228.

    Google Scholar 

  • Lustyk, M. K. B., Gerrish, W. G., Shaver, S., & Keys, S. L. (2009). Cognitive-behavioral therapy for premenstrual syndrome and premenstrual dysphoric disorder: A systematic review. Archives of Women's Mental Health, 12(2), 85–96. doi:10.1007/s00737-009-0052-y.

    Google Scholar 

  • Lustyk, M. K. B., Widman, L., & Becker Lde, L. (2007). Abuse history and premenstrual symptomatology: Assessing the mediating role of perceived stress. Women & Health, 46(4), 61–80.

    Google Scholar 

  • Magnay, J. L., El-Shourbagy, M., Fryer, A. A., O’Brien, S., & Ismail, K. M. K. (2010). Analysis of the serotonin transporter promoter rs25531 polymorphism in premenstrual dysphoric disorder. American Journal of Obstetrics and Gynecology, 203(2), 181.e1–5. doi:10.1016/j.ajog.2010.02.043

  • Magnay, J. L., Ismail, K. M. K., Chapman, G., Cioni, L., Jones, P. W., & O’Brien, S. (2006). Serotonin transporter, tryptophan hydroxylase, and monoamine oxidase A gene polymorphisms in premenstrual dysphoric disorder. American Journal of Obstetrics and Gynecology, 195(5), 1254–1259. doi:10.1016/j.ajog.2006.06.087.

    Google Scholar 

  • Majewska, M. D., Harrison, N. L., Schwartz, R. D., Barker, J. L., & Paul, S. M. (1986). Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science (New York, N.Y.), 232(4753), 1004–1007.

    Google Scholar 

  • Markou, E., Boura, E., Tsalikis, L., Deligianidis, A., & Konstantinidis, A. (2011). The influence of sex hormones on proinflammatory cytokines in gingiva of periodontally healthy premenopausal women. Journal of Periodontal Research, 46(5), 528–532. doi:10.1111/j.1600-0765.2011.01369.x.

    Google Scholar 

  • Maswood, S., Truitt, W., Hotema, M., Caldarola-Pastuszka, M., & Uphouse, L. (1999). Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: Role of the serotonin transporter and terminal autoreceptors. Brain Research, 831(1–2), 146–154.

    Google Scholar 

  • McQueen, J. K., Wilson, H., & Fink, G. (1997). Estradiol-17 beta increases serotonin transporter (SERT) mRNA levels and the density of SERT-binding sites in female rat brain. Brain Research. Molecular Brain Research, 45(1), 13–23.

    Google Scholar 

  • Menkes, D. B., Coates, D. C., & Fawcett, J. P. (1994). Acute tryptophan depletion aggravates premenstrual syndrome. Journal of Affective Disorders, 32(1), 37–44.

    Google Scholar 

  • Morse, C. A., Dudley, E., Guthrie, J., & Dennerstein, L. (1998). Relationships between premenstrual complaints and perimenopausal experiences. Journal of Psychosomatic Obstetrics and Gynaecology, 19(4), 182–191.

    Google Scholar 

  • Nillni, Y. I., Toufexis, D. J., & Rohan, K. J. (2011). Anxiety sensitivity, the menstrual cycle, and panic disorder: A putative neuroendocrine and psychological interaction. Clinical Psychology Review, 31(7), 1183–1191. doi:10.1016/j.cpr.2011.07.006.

    Google Scholar 

  • Northoff, H., Symons, S., Zieker, D., Schaible, E. V., Schäfer, K., Thoma, S., … Fehrenbach, E. (2008). Gender- and menstrual phase dependent regulation of inflammatory gene expression in response to aerobic exercise. Exercise Immunology Review, 14, 86–103.

    Google Scholar 

  • O’Brien, P. M. S., Bäckström, T., Brown, C., Dennerstein, L., Endicott, J., Epperson, C. N., … Yonkers, K. (2011). Towards a consensus on diagnostic criteria, measurement and trial design of the premenstrual disorders: The ISPMD Montreal consensus. Archives of Women’s Mental Health, 14(1), 13–21. doi:10.1007/s00737-010-0201-3

  • O’Brien, S. M., Fitzgerald, P., Scully, P., Landers, A., Scott, L. V., & Dinan, T. G. (2007). Impact of gender and menstrual cycle phase on plasma cytokine concentrations. Neuroimmunomodulation, 14(2), 84–90. doi:10.1159/000107423.

    Google Scholar 

  • Paddison, P. L., Gise, L. H., Lebovits, A., Strain, J. J., Cirasole, D. M., & Levine, J. P. (1990). Sexual abuse and premenstrual syndrome: Comparison between a lower and higher socioeconomic group. Psychosomatics, 31(3), 265–272. doi:10.1016/S0033-3182(90)72162-7.

    Google Scholar 

  • Perkonigg, A., Yonkers, K. A., Pfister, H., Lieb, R., & Wittchen, H.-U. (2004). Risk factors for premenstrual dysphoric disorder in a community sample of young women: The role of traumatic events and posttraumatic stress disorder. The Journal of Clinical Psychiatry, 65(10), 1314–1322.

    Google Scholar 

  • Pico-Alfonso, M. A., Mastorci, F., Ceresini, G., Ceda, G. P., Manghi, M., Pino, O., … Sgoifo, A. (2007). Acute psychosocial challenge and cardiac autonomic response in women: The role of estrogens, corticosteroids, and behavioral coping styles. Psychoneuroendocrinology, 32(5), 451–463. doi:10.1016/j.psyneuen.2007.02.009

  • Pilver, C. E., Levy, B. R., Libby, D. J., & Desai, R. A. (2011). Posttraumatic stress disorder and trauma characteristics are correlates of premenstrual dysphoric disorder. Archives of Women's Mental Health, 14(5), 383–393. doi:10.1007/s00737-011-0232-4.

    Google Scholar 

  • Potter, J., Bouyer, J., Trussell, J., & Moreau, C. (2009). Premenstrual syndrome prevalence and fluctuation over time: Results from a French population-based survey. Journal of Women's Health (2002), 18(1), 31–39. doi:10.1089/jwh.2008.0932.

    Google Scholar 

  • Protopopescu, X., Tuescher, O., Pan, H., Epstein, J., Root, J., Chang, L., … Silbersweig, D. (2008). Toward a functional neuroanatomy of premenstrual dysphoric disorder. Journal of Affective Disorders, 108(1–2), 87–94. doi:10.1016/j.jad.2007.09.015

  • Puder, J. J., Blum, C. A., Mueller, B., De Geyter, C., Dye, L., & Keller, U. (2006). Menstrual cycle symptoms are associated with changes in low-grade inflammation. European Journal of Clinical Investigation, 36(1), 58–64. doi:10.1111/j.1365-2362.2006.01591.x.

    Google Scholar 

  • Rabin, D. S., Schmidt, P. J., Campbell, G., Gold, P. W., Jensvold, M., Rubinow, D. R., & Chrousos, G. P. (1990). Hypothalamic-pituitary-adrenal function in patients with the premenstrual syndrome. Journal of Clinical Endocrinology and Metabolism, 71(5), 1158–1162.

    Google Scholar 

  • Raison, C. L., Capuron, L., & Miller, A. H. (2006). Cytokines sing the blues: Inflammation and the pathogenesis of depression. Trends in Immunology, 27(1), 24–31. doi:10.1016/j.it.2005.11.006.

    Google Scholar 

  • Rapkin, A. J., Berman, S. M., Mandelkern, M. A., Silverman, D. H. S., Morgan, M., & London, E. D. (2011). Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorder. Biological Psychiatry, 69(4), 374–380. doi:10.1016/j.biopsych.2010.09.029.

    Google Scholar 

  • Rapkin, A. J., Edelmuth, E., Chang, L. C., Reading, A. E., McGuire, M. T., & Su, T. P. (1987). Whole-blood serotonin in premenstrual syndrome. Obstetrics and Gynecology, 70(4), 533–537.

    Google Scholar 

  • Rasgon, N., McGuire, M., Tanavoli, S., Fairbanks, L., & Rapkin, A. (2000). Neuroendocrine response to an intravenous L-tryptophan challenge in women with premenstrual syndrome. Fertility and Sterility, 73(1), 144–149.

    Google Scholar 

  • Ravindran, L. N., Woods, S.-A., Steiner, M., & Ravindran, A. V. (2007). Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): A case series. Archives of Women's Mental Health, 10(3), 125–127. doi:10.1007/s00737-007-0181-0.

    Google Scholar 

  • Reame, N. E., Marshall, J. C., & Kelch, R. P. (1992). Pulsatile LH secretion in women with premenstrual syndrome (PMS): Evidence for normal neuroregulation of the menstrual cycle. Psychoneuroendocrinology, 17(2–3), 205–213.

    Google Scholar 

  • Reed, S. C., Levin, F. R., & Evans, S. M. (2008). Changes in mood, cognitive performance, and appetite in the late luteal and follicular phases of the menstrual cycle in women with and without PMDD (premenstrual dysphoric disorder). Hormones and Behavior, 54(1), 185–193. doi:10.1016/j.yhbeh.2008.02.018.

    Google Scholar 

  • Rehavi, M., Goldin, M., Roz, N., & Weizman, A. (1998). Regulation of rat brain vesicular monoamine transporter by chronic treatment with ovarian hormones. Brain Research. Molecular Brain Research, 57(1), 31–37.

    Google Scholar 

  • Rohleder, N., Wolf, J. M., Piel, M., & Kirschbaum, C. (2003). Impact of oral contraceptive use on glucocorticoid sensitivity of pro-inflammatory cytokine production after psychosocial stress. Psychoneuroendocrinology, 28(3), 261–273. doi:10.1016/S0306-4530(02)00019-7.

    Google Scholar 

  • Rubinow, D. R., Hoban, M. C., Grover, G. N., Galloway, D. S., Roy-Byrne, P., Andersen, R., & Merriam, G. R. (1988). Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects. American Journal of Obstetrics and Gynecology, 158(1), 5–11.

    Google Scholar 

  • Sacco, S., Ricci, S., Degan, D., & Carolei, A. (2012). Migraine in women: The role of hormones and their impact on vascular diseases. The Journal of Headache and Pain, 13(3), 177–189. doi:10.1007/s10194-012-0424-y.

    Google Scholar 

  • Schatz, D. B., Hsiao, M.-C., & Liu, C.-Y. (2012). Premenstrual dysphoric disorder in East Asia: A review of the literature. International Journal of Psychiatry in Medicine, 43(4), 365–380.

    Google Scholar 

  • Schmidt, P. J., Grover, G. N., Hoban, M. C., & Rubinow, D. R. (1990). State-dependent alterations in the perception of life events in menstrual-related mood disorders. The American Journal of Psychiatry, 147(2), 230–234.

    Google Scholar 

  • Schmidt, P. J., Nieman, L. K., Danaceau, M. A., Adams, L. F., & Rubinow, D. R. (1998). Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome. The New England Journal of Medicine, 338(4), 209–216. doi:10.1056/NEJM199801223380401.

    Google Scholar 

  • Schneider, T., & Popik, P. (2009). An animal model of premenstrual dysphoric disorder sensitive to antidepressants. Current Protocols in Neuroscience/Editorial Board, Jacqueline N. Crawley … [et al.], Chapter 9, Unit 9.31. doi:10.1002/0471142301.ns0931s46

  • Segebladh, B., Bannbers, E., Kask, K., Nyberg, S., Bixo, M., Heimer, G., & Sundström-Poromaa, I. (2011). Prevalence of violence exposure in women with premenstrual dysphoric disorder in comparison with other gynecological patients and asymptomatic controls. Acta Obstetricia et Gynecologica Scandinavica, 90(7), 746–752. doi:10.1111/j.1600-0412.2011.01151.x

  • Segebladh, B., Bannbers, E., Moby, L., Nyberg, S., Bixo, M., Bäckström, T., & Sundström Poromaa, I. (2013). Allopregnanolone serum concentrations and diurnal cortisol secretion in women with premenstrual dysphoric disorder. Archives of Women’s Mental Health. doi:10.1007/s00737-013-0327-1

  • Shah, N. R., Jones, J. B., Aperi, J., Shemtov, R., Karne, A., & Borenstein, J. (2008). Selective serotonin reuptake inhibitors for premenstrual syndrome and premenstrual dysphoric disorder: A meta-analysis. Obstetrics and Gynecology, 111(5), 1175–1182. doi:10.1097/AOG.0b013e31816fd73b.

    Google Scholar 

  • Sherwin, B. B., & Suranyi-Cadotte, B. E. (1990). Up-regulatory effect of estrogen on platelet 3H-imipramine binding sites in surgically menopausal women. Biological Psychiatry, 28(4), 339–348.

    Google Scholar 

  • Shourie, V., Dwarakanath, C. D., Prashanth, G. V., Alampalli, R. V., Padmanabhan, S., & Bali, S. (2012). The effect of menstrual cycle on periodontal health—a clinical and microbiological study. Oral Health & Preventive Dentistry, 10(2), 185–192.

    Google Scholar 

  • Smith, Adams, Schmidt, Rubinow, & Wassermann (2003). Abnormal luteal phase excitability of the motor cortex in women with premenstrual syndrome. Biol Psychiatry. 54(7):757–62.

    Google Scholar 

  • Smith, M., Poschman, K., Cavaleri, M., Howell, H., & Yonkers, K. (2006). Symptoms of posttraumatic stress disorder in a community sample of low-income pregnant women. American Journal of Psychiatry, 163(5), 881–884.

    Google Scholar 

  • Steinberg, E. M., Cardoso, G. M. P., Martinez, P. E., Rubinow, D. R., & Schmidt, P. J. (2012). Rapid response to fluoxetine in women with premenstrual dysphoric disorder. Depression and Anxiety, 29(6), 531–540. doi:10.1002/da.21959.

    Google Scholar 

  • Stone, S. E., Mazmanian, D., Oinonen, K. A., & Sharma, V. (2013). Past reproductive events as predictors of physical symptom severity during the menopausal transition. Menopause (New York, N.Y.). doi:10.1097/GME.0b013e31827e18b8.

    Google Scholar 

  • Strine, T. W., Chapman, D. P., & Ahluwalia, I. B. (2005). Menstrual-related problems and psychological distress among women in the United States. Journal of Women's Health (2002), 14(4), 316–323. doi:10.1089/jwh.2005.14.316.

    Google Scholar 

  • Sugawara, M., Toda, M. A., Shima, S., Mukai, T., Sakakura, K., & Kitamura, T. (1997). Premenstrual mood changes and maternal mental health in pregnancy and the postpartum period. Journal of Clinical Psychology, 53(3), 225–232.

    Google Scholar 

  • Sundström, I., Ashbrook, D., & Bäckström, T. (1997). Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: A pilot study. Psychoneuroendocrinology, 22(1), 25–38.

    Google Scholar 

  • Sundström, I., & Bäckström, T. (1998a). Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects. Biological Psychiatry, 44(8), 755–764.

    Google Scholar 

  • Sundström, I., & Bäckström, T. (1998b). Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: An open trial. Psychoneuroendocrinology, 23(1), 73–88.

    Google Scholar 

  • Sundström, I., Nyberg, S., & Bäckström, T. (1997). Patients with premenstrual syndrome have reduced sensitivity to midazolam compared to control subjects. Neuropsychopharmacology, 17(6), 370–381. doi:10.1016/S0893-133X(97)00086-9.

    Google Scholar 

  • Sylvén, S. M., Ekselius, L., Sundström-Poromaa, I., & Skalkidou, A. (2013). Premenstrual syndrome and dysphoric disorder as risk factors for postpartum depression. Acta Obstetricia et Gynecologica Scandinavica, 92(2), 178–184. doi:10.1111/aogs.12041.

    Google Scholar 

  • Takeda, T., Tasaka, K., Sakata, M., & Murata, Y. (2006). Prevalence of premenstrual syndrome and premenstrual dysphoric disorder in Japanese women. Archives of Women's Mental Health, 9(4), 209–212. doi:10.1007/s00737-006-0137-9.

    Google Scholar 

  • Thys-Jacobs, S., McMahon, D., & Bilezikian, J. P. (2008). Differences in free estradiol and sex hormone-binding globulin in women with and without premenstrual dysphoric disorder. The Journal of Clinical Endocrinology and Metabolism, 93(1), 96–102. doi:10.1210/jc.2007-1726.

    Google Scholar 

  • Timby, E., Balgård, M., Nyberg, S., Spigset, O., Andersson, A., Porankiewicz-Asplund, J., … Poromaa, I. S. (2006). Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. Psychopharmacology, 186(3), 414–424. doi:10.1007/s00213-005-0148-7

  • Treloar, S. A., Heath, A. C., & Martin, N. G. (2002). Genetic and environmental influences on premenstrual symptoms in an Australian twin sample. Psychological Medicine, 32(1), 25–38.

    Google Scholar 

  • Tschudin, S., Bertea, P. C., & Zemp, E. (2010). Prevalence and predictors of premenstrual syndrome and premenstrual dysphoric disorder in a population-based sample. Archives of Women's Mental Health, 13(6), 485–494. doi:10.1007/s00737-010-0165-3.

    Google Scholar 

  • Turkmen, S., Backstrom, T., Wahlstrom, G., Andreen, L., & Johansson, I.-M. (2011). Tolerance to allopregnanolone with focus on the GABA-A receptor. British Journal of Pharmacology, 162(2), 311–327. doi:10.1111/j.1476-5381.2010.01059.x.

    Google Scholar 

  • van den Akker, O. B., Stein, G. S., Neale, M. C., & Murray, R. M. (1987). Genetic and environmental variation in menstrual cycle: Histories of two British twin samples. Acta Geneticae Medicae et Gemellologiae, 36(4), 541–548.

    Google Scholar 

  • van Veen, J. F., Jonker, B. W., van Vliet, I. M., & Zitman, F. G. (2009). The effects of female reproductive hormones in generalized social anxiety disorder. International Journal of Psychiatry in Medicine, 39(3), 283–295.

    Google Scholar 

  • Wander, K., Brindle, E., & O’Connor, K. A. (2008). C-reactive protein across the menstrual cycle. American Journal of Physical Anthropology, 136(2), 138–146. doi:10.1002/ajpa.20785.

    Google Scholar 

  • Wang, M., Seippel, L., Purdy, R. H., & Bãckström, T. (1996). Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one. The Journal of Clinical Endocrinology and Metabolism, 81(3), 1076–1082.

    Google Scholar 

  • Watson, C. S., Alyea, R. A., Cunningham, K. A., & Jeng, Y.-J. (2010). Estrogens of multiple classes and their role in mental health disease mechanisms. International Journal of Women’s Health, 2, 153–166.

    Google Scholar 

  • WHO, W. H. O. (2004). The ICD-1 classification of mental, behavioral and developmental disorders (2nd ed., 10th revision). Geneva, Switzerland.

    Google Scholar 

  • Wihlbäck, A.-C., Sundström Poromaa, I., Bixo, M., Allard, P., Mjörndal, T., & Spigset, O. (2004). Influence of menstrual cycle on platelet serotonin uptake site and serotonin2A receptor binding. Psychoneuroendocrinology, 29(6), 757–766. doi:10.1016/S0306-4530(03)00120-3.

    Google Scholar 

  • Wittchen, H. U., Becker, E., Lieb, R., & Krause, P. (2002). Prevalence, incidence and stability of premenstrual dysphoric disorder in the community. Psychological Medicine, 32(1), 119–132.

    Google Scholar 

  • Wium-Andersen, M. K., Ørsted, D. D., Nielsen, S. F., & Nordestgaard, B. G. (2013). Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry, 70(2), 176–184. doi:10.1001/2013.jamapsychiatry.102.

    Google Scholar 

  • Wyatt, K. M., Dimmock, P. W., Ismail, K. M. K., Jones, P. W., & O’Brien, P. M. S. (2004). The effectiveness of GnRHa with and without “add-back” therapy in treating premenstrual syndrome: A meta analysis. BJOG, 111(6), 585–593. doi:10.1111/j.1471-0528.2004.00135.x.

    Google Scholar 

  • Wyatt, K., Dimmock, P., Jones, P., Obhrai, M., & O’Brien, S. (2001). Efficacy of progesterone and progestogens in management of premenstrual syndrome: Systematic review. BMJ (Clinical Research ed.), 323(7316), 776–780.

    Google Scholar 

  • Yamamoto, K., Okazaki, A., Sakamoto, Y., & Funatsu, M. (2009). The relationship between premenstrual symptoms, menstrual pain, irregular menstrual cycles, and psychosocial stress among Japanese college students. Journal of Physiological Anthropology, 28(3), 129–136.

    Google Scholar 

  • Yang, M., Wallenstein, G., Hagan, M., Guo, A., Chang, J., & Kornstein, S. (2008). Burden of premenstrual dysphoric disorder on health-related quality of life. Journal of Women’s Health (2002), 17(1), 113–121. doi:10.1089/jwh.2007.0417.

    Google Scholar 

  • Yonkers, K. A. (1997). Anxiety symptoms and anxiety disorders: How are they related to premenstrual disorders? Journal of Clinical Psychiatry, 58(Suppl. 3), 62–67; discussion 68–69.

    Google Scholar 

  • Yonkers, K. A., Holthausen, G. A., Poschman, K., & Howell, H. B. (2006). Symptom-onset treatment for women with premenstrual dysphoric disorder. Journal of Clinical Psychopharmacology, 26(2), 198–202. doi:10.1097/01.jcp.0000203197.03829.ae.

    Google Scholar 

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  1. Penn Center for Women’s Behavioral Wellness, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    C. Neill Epperson M.D. & Liisa Hantsoo Ph.D.

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    Diana Lynn Barnes

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Epperson, C.N., Hantsoo, L. (2014). Menstruation and Premenstrual Dysphoric Disorder: Its Impact on Mood. In: Barnes, D. (eds) Women's Reproductive Mental Health Across the Lifespan. Springer, Cham. https://doi.org/10.1007/978-3-319-05116-1_3

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