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Effects of Psychotropic Drugs on the EEG

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Standard EEG: A Research Roadmap for Neuropsychiatry

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Abstract

The focus of this chapter is on the common clinical situation where a patient who is suffering from a chronic psychiatric disorder (and at times multiple co-morbid psychiatric and medical conditions), and is receiving a number of CNS active medications begins to exhibit signs of clinical deterioration. In such conditions, it is crucially important to determine the possible factors contributing to the worsening clinical condition.

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References

  • Bellesi M, Passamonti L, Silvestrini M, Bartolini M, Provinciali L (2006) Non-convlusive status epilepticus during lithium treatment at therapeutic doses. Neurol Sci 26(6):444–446

    Article  CAS  PubMed  Google Scholar 

  • Boora K, Xu J, Hyatt J (2008) Encephalopathy with combined lithium—risperidone administration. Acta Psychiatr Scand 117(5):394–395

    Article  CAS  PubMed  Google Scholar 

  • Camacho A, Garcia-Navvaro M, Marinez B (2005) Olanzapine induced myoclonic status. Clin Neuropharmacol 28:145–147

    Article  PubMed  Google Scholar 

  • Centorrino F, Price BH, Tuttle M, Bahk WM et al (2002) EEG abnormalities during treatment with typical and atypical antipsychotics. Am J Psychiatry 159:109–115

    Article  PubMed  Google Scholar 

  • Cook BL, Shukla S, Hoff A (1986) EEG abnormalities in bipolar affective disorder. J Affect Disord 11:147–149

    Article  CAS  PubMed  Google Scholar 

  • Dalen P (1965) Family history, the electroencephalogram and perinatal factors in manic conditions. Acta Psychiatr Scand 41:527–563

    Article  CAS  PubMed  Google Scholar 

  • Dasberg H, Robinson S (1969a) Isr Ann Psychiatry 7:185–200

    CAS  Google Scholar 

  • Dasberg H, Robinson S (1969b) Isr Ann Psychiatry 7:201–212

    Google Scholar 

  • Dasberg H, Robinson S (1971) Electroencephalographic variations following anti-psychotic drug treatment (diagnostic and prognostic significance) Dis Nerv Sys July; 472–478

    Google Scholar 

  • Drinkinburg WHIM, Ruigt GSF, Jobert M (eds) (2004) Essentials and applications of EEG research in preclinical and clinical pharmacology. IPEG, Berlin

    Google Scholar 

  • Garcia-Solana MI, Rodrigo-Sesma A, Garcia Rodriguez V et al (2004) Rev Neurol 39(6):595–597

    Google Scholar 

  • Helmchen H (1974) Significance of psychotropic drug-induced abnormal EEGs. In: Turan Itil (Ed) Psychotropic drugs and human EEG Mod. Probl. Pharmacopsychiat, vol 8.Krager, New York, pp 317–326

    Google Scholar 

  • Ikeda A, Kato D (2003) Biological predictors of lithium response in bipolar disorder. Psychiatry Clin Neurosci 57:243–250

    Article  CAS  PubMed  Google Scholar 

  • Ikeda A, Kato N, Kato T (2002) Possible relationship between electroencephalogram finding and lithium response in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 26:903–907

    Article  CAS  PubMed  Google Scholar 

  • Kadrmas A, Winokur G (1979) Manic depressive illness and EEG abnormalities. J Clin Psychiatry 40:306–307

    CAS  PubMed  Google Scholar 

  • Kaplan PW, Birbeck G (2006) Lithium induced confusianal states: non-convulsive status epilepticus or triphasic encephalopathy. Epilepsia 47(12):2071–2074

    Article  CAS  PubMed  Google Scholar 

  • Kugler J, Lorenzi E, Spatz R, Zimmermann H (1979) Dug-induced paroxysmal EEG-activities. Pharmakopsychiat 12:165–172

    Article  CAS  Google Scholar 

  • Pittmann F, Schlote K, Broich K, Marneros A (2000) Electroencephalogram alterations during treatment with olanzapine. Psychopharmacology 150(2):216–219

    Article  Google Scholar 

  • Reeves RR, Struve FA, Patrick G (2001) Does EEG predict response to valproate versus lithium patients with mania? Ann Clin Psychiatry 13:69–73

    Article  CAS  PubMed  Google Scholar 

  • Small JG, Milstein V, Perez HC, Small IF, Moore DF (1972) EEG and neurophysiological studies of lithium in normal volunteers. Biol Psychiat 5:65–77

    CAS  PubMed  Google Scholar 

  • Small JG, Milstein V, Medlock CE (1997) Clinical EEG findings in mania. Clin Electroencephalogr 28:229–235

    CAS  PubMed  Google Scholar 

  • Small JG, Milstein V, Malloy FW, Klapper MH, Golay SJ, Medlock CE (1998) Topographic EEG studies of mania. Clin Electroencephalogr 29:59–66

    CAS  PubMed  Google Scholar 

  • Small JG, Milstein V, Malloy FW, Medlock CE, Klapper MH (1999) Clinical and quantitative EEG studies of mania. J Affect Disord 53:217–224

    Article  CAS  PubMed  Google Scholar 

  • Suda M, Kubota F, Aihara Y, Hiraoka T, Aoyama Y, Hattori S, Fukoda M, Mikuni M (2009) A case of lithium intoxication with periodic sharp waves. Pharmacopsychiatry 42:122–123

    Article  CAS  PubMed  Google Scholar 

  • Taylor MA, Abrams R (1980) Familial and non-familial mania. J Affect Disord 2:111–118

    Article  CAS  PubMed  Google Scholar 

  • Van Sweden B, Dumon-Radermecker M (1982) The EEG in chronic psychotropic drug intoxications. Clin EEG 13:206–215

    Google Scholar 

  • Wichniak A, Szafranski T, Wierzbicka A et al (2006) Electroencephalogram slowing, sleepiness and treatment response in patients with schizophrenia during olanzapine treatment. J Psychopharmacology 20:80–85

    Article  CAS  Google Scholar 

  • Yip KK, Yeung WT (2007) Lithium overdose causing non-convulsive status epilepticus; the importance of lithium level and the electroencephalogram in diagnosis. Hong Kong Med J 13:471–474

    CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Psychiatry, University of Missouri-Kansas City School of Medicine (UMKC), Kansas, MO, USA

    Nash N. Boutros

  2. The Center for Behavioral Medicine, University of Missouri-Kansas City School of Medicine (UMKC), 1000 East 24th Street, Kansas, MO, 64108, USA

    Nash N. Boutros

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  1. Nash N. Boutros
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Correspondence to Nash N. Boutros .

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Boutros, N.N. (2013). Effects of Psychotropic Drugs on the EEG. In: Standard EEG: A Research Roadmap for Neuropsychiatry. Springer, Cham. https://doi.org/10.1007/978-3-319-04444-6_4

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