Abstract
There are only a few papers devoted to studying of cerebral blood flow by CT perfusion in severe traumatic brain injury, with first publications appearing recently. However, no data are available on dynamic CT perfusion of the regional cerebral blood flow in hemispheric structures, subcortical formations, and brain stem in comatose patients at different stages of consciousness recovery.
In this work CT perfusion was used to evaluate the regional cerebral blood flow with regard to focal and diffuse morphological changes of the brain in severe trauma. Our studies showed that mosaic and multidirectional alterations of the cerebral blood flow may range from oligemia-ischemia in one vascular region to hyperemia in the other in dynamics of the traumatic brain disease. All patients in the analyzed group revealed regional cerebral blood flow values beyond the normal range in the first and repeated CT perfusion examinations.
Quantitative blood flow parameters in the brain stem have been studied by CT perfusion in comatose patients, with regard to dynamics of the traumatic brain disease and its outcome.
This chapter has been contributed in collaboration with Eugenia Alexandrova and Gleb Danilov.
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Zakharova, N., Kornienko, V., Potapov, A., Pronin, I. (2014). Dynamics of Hemispheric and Brain Stem Regional Cerebral Blood Flow. In: Neuroimaging of Traumatic Brain Injury. Springer, Cham. https://doi.org/10.1007/978-3-319-04355-5_6
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DOI: https://doi.org/10.1007/978-3-319-04355-5_6
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