Abstract
In Chapter 3 we discuss the results of correlation study between severity, location, and level of hemispheric and brain stem damage based on clinical, CT, and MRI comparison analysis. CT and MRI data were compared to determine sensitivity and possibilities in detecting brain lesion location and severity based on the mechanisms of injury, trauma severity, and outcome. MRI data were used for a more differentiated evaluation of hemispheric and brain stem damages.
Today it is still unclear what localizations and severity of traumatic brain injury may cause disorders of consciousness and development of coma with variable depth and duration. It equally applies not only to the brain stem but also to the thalamus, basal ganglia, corpus callosum, and cortical-subcortical structures.
To answer this question 162 patients with acute and subacute TBI of various severity were examined by different sequences of magnetic resonance imaging. A comprehensive MRI classification of localization of the brain stem and hemispheric damages has been proposed. This classification significantly correlates with Glasgow Coma Scale and Glasgow Outcome Scale, thus proving its prognostic value. The classification developed for the brain injury localization and levels based on MRI data may become a useful tool for forming the data bank on traumatic brain injury and studying clinical comparative evaluations of efficacy of various approaches for the management of patients with severe TBI.
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This chapter has been contributed in collaboration with Eugenia Alexandrova and Gleb Danilov
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Zakharova, N., Kornienko, V., Potapov, A., Pronin, I. (2014). Neuroimaging Classification of Traumatic Brain Injury. In: Neuroimaging of Traumatic Brain Injury. Springer, Cham. https://doi.org/10.1007/978-3-319-04355-5_3
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