Abstract
AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investigation into the degree of activation and deactivation of AMPK subunits under exercise can provide valuable data for understanding AMPK. In particular, the effect of AMPK on muscle cellular energy status makes this protein a promising pharmacological target for disease treatment. As more AMPK regulation data are accumulated, data mining techniques can play an important role in identifying frequent patterns in the data. Association rule mining, which is commonly used in market basket analysis, can be applied to AMPK regulation.
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© 2014 Springer International Publishing Switzerland
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Chen, Q., Chen, B., Zhang, C. (2014). Exploration of Positive Frequent Patterns for AMP-Activated Protein Kinase Regulation. In: Chen, Q., Chen, B., Zhang, C. (eds) Intelligent Strategies for Pathway Mining. Lecture Notes in Computer Science(), vol 8335. Springer, Cham. https://doi.org/10.1007/978-3-319-04172-8_4
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DOI: https://doi.org/10.1007/978-3-319-04172-8_4
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-04171-1
Online ISBN: 978-3-319-04172-8
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