Skip to main content

Boekelheide reaction

  • Chapter
  • First Online:
Name Reactions
  • 356 Accesses

Abstract

Treatment of 2-methylpyridine N-oxide with trifluoroacetic anhydride, or acetic anhydride gives rise to 2-hydroxymethylpyridine.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Boekelheide, V.; Linn, W. J. J. Am. Chem. Soc. 1954, 76, 1286−1291. Virgil Boekelheide (1919−2003) was a professor at the University of Oregon.

    Google Scholar 

  2. Boekelheide, V.; Harrington, D. L. Chem. Ind. 1955, 1423−1424.

    Google Scholar 

  3. Katritzky, A. R.; Lagowski, J. M. Chemistry of the Heterocylic N-Oxides, Academic Press: NY, 1971. (Review).

    Google Scholar 

  4. Newkome, G. R.; Theriot, K. J.; Gupta, V. K.; Fronczek, F. R.; Baker, G. R. J. Org. Chem. 1989, 54, 1766−1769.

    Article  CAS  Google Scholar 

  5. Katritzky, A. R.; Lam, J. N. Heterocycles 1992, 33, 1011−1049. (Review).

    Google Scholar 

  6. Fontenas, C.; Bejan, E.; Haddou, H. A.; Balavoine, G. G. A. Synth. Commun. 1995, 25, 629−633.

    Article  CAS  Google Scholar 

  7. Galatsis, P. Boekelheide Reaction. In Name Reactions in Heterocyclic Chemistry; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2005, pp 340−349. (Review).

    Google Scholar 

  8. Havas, F.; Danel, M.; Galaup, C.; Tisnès, P.; Picard, C. Tetrahedron Lett. 2007, 48, 999−1002.

    Article  CAS  Google Scholar 

  9. Dai, L.; Fan, D.; Wang, X.; Chen, Y. Synth. Commun. 2008, 38, 576−582.

    Article  CAS  Google Scholar 

  10. Das, S. K.; Frey, J. Tetrahedron Lett. 2012, 53, 3869−3872.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Li, J.J. (2014). Boekelheide reaction. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_30

Download citation

Publish with us

Policies and ethics