Abstract
Ring opening of oxiranes using azide followed by PPh3 reduction of the intermediate azido alcohol to give the corresponding aziridines. Cf. Staudinger reduction.
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References
Ittah, Y.; Sasson, Y.; Shahak, I.; Tsaroom, S.; Blum, J. J. Org. Chem. 1978, 43, 4271– 4273. Jochanan Blum is a professor at The Hebrew University in Jerusalem, Israel.
Tanner, D.; Somfai, P. Tetrahedron Lett. 1987, 28, 1211–1214.
Wipf, P.; Venkatraman, S.; Miller, C. P. Tetrahedron Lett. 1995, 36, 3639–3642.
Regueiro-Ren, A.; Borzilleri, R. M.; Zheng, X.; Kim, S.-H.; Johnson, J. A.; Fairchild, C. R.; Lee, F. Y. F.; Long, B. H.; Vite, G. D. Org. Lett. 2001, 3, 2693–2696.
Fürmeier, S.; Metzger, J. O. Eur. J. Org. Chem. 2003, 649–659.
Oh, K.; Parsons, P. J.; Cheshire, D. Synlett 2004, 2771–2775.
Serafin, S. V.; Zhang, K.; Aurelio, L.; Hughes, A. B.; Morton, T. H. Org. Lett. 2004, 6, 1561–1564.
Torrado, A. Tetrahedron Lett. 2006, 47, 7097–7100.
Pulipaka, A. B.; Bergmeier, S. C. J. Org. Chem. 2008, 73, 1462–1467.
Richter, J. M. Blum aziridine synthesis, In Name Reactions in Heterocyclic Chemistry II; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2011, pp 2–10. (Review).
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Li, J.J. (2014). Blum–Ittah aziridine synthesis. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_29
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DOI: https://doi.org/10.1007/978-3-319-03979-4_29
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