Skip to main content

How to Choose the Number of Gradient Directions for Estimation Problems from Noisy Diffusion Tensor Data

  • Conference paper
  • First Online:
Book cover Contemporary Developments in Statistical Theory

Part of the book series: Springer Proceedings in Mathematics & Statistics ((PROMS,volume 68))

Abstract

We consider two popular nonparametric models describing measurements obtained from low and high angular resolution diffusion tensor imaging. The balance between the number of distinct directions for measurements and the number of repetitions is investigated from the statistical point of view. We show that designs with multiple independent repetitions using one set of six directions for the low resolution case yield smaller norms of the estimator’s covariance function than designs where a large set of directions with no repetitions is used, assuming that norms of covariances of image components are similar for both types of designs. The difference is inversely proportional to the number of repetitions. Similar result is obtained for the high resolution case. This yields a practical guideline on how to choose the number of gradient directions and the number of repetitions for estimation problems in this imaging context.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Assemlal H-E, Tschumperle D, Brun L, Siddiqi K (2011) Recent advances in diffusion MRI modeling: angular and radial reconstruction. Med Image An 15:369–396

    Article  Google Scholar 

  • Basser P, Pierpaoli C A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med 39:928–934

    Google Scholar 

  • Descoteaux M, Angelino E, Fitzgibbons S, Deriche R (2006) Apparent diffusion coefficients from high angular resolution diffusion imaging: estimation and applications. Magn Reson Med 56 (2):395–410

    Article  Google Scholar 

  • Koltchinskii V, Sakhanenko L, Cai S (2007) Integral curves of noisy vector fields and statistical problems in diffusion tensor imaging: nonparametric kernel estimation and hypotheses testing. Ann Stat 35:1576–1607

    Article  MATH  MathSciNet  Google Scholar 

  • Özarslan E, Mareci T (2003) Generalized diffusion tensor imaging and analytical relationships between diffusion tensor imaging and high angular resolution diffusion imaging. Magn Reson Med 50(5):955–965

    Article  Google Scholar 

  • Zhu H, Zhang H, Ibrahim J, Peterson B (2007) Statistical analysis of diffusion tensors in diffusion-weighted magnetic resonance image data. J. Amer Stat Assoc102:1081–1110

    Google Scholar 

  • Zhu H, Li Y, Ibrahim I, Shi X, An H, Chen Y, Gao W, Lin W, Rowe D, Peterson B (2009) Regression models for identifying noise sources in magnetic resonance images. J Amer Stat Assoc 104:623–637

    Article  MathSciNet  Google Scholar 

Download references

Acknowledgement

Research is partially supported by NSF grant DMS-1208238. The author is grateful to professor Hira Koul for his guidance, help, and contagious enthusiasm for statistics.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lyudmila Sakhanenko .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this paper

Cite this paper

Sakhanenko, L. (2014). How to Choose the Number of Gradient Directions for Estimation Problems from Noisy Diffusion Tensor Data. In: Lahiri, S., Schick, A., SenGupta, A., Sriram, T. (eds) Contemporary Developments in Statistical Theory. Springer Proceedings in Mathematics & Statistics, vol 68. Springer, Cham. https://doi.org/10.1007/978-3-319-02651-0_19

Download citation

Publish with us

Policies and ethics