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Genes and Hormones: What Make Up an Individual’s Sex

Chapter
Part of the Crossroads of Knowledge book series (CROKNOW, volume 1)

Abstract

The twentieth century has assisted the conceptual and practical separation of the terms sex and gender so as to have better tools to address what are considered biological factors versus social factors. The biological construction of sex has delved deeper into the body, beyond the mere genitals, to expose not only reproductive organs and gonads but also molecular components such as hormones, chromosomes, and genes. Since the scientific “discovery” of the sex chromosomes, XY and XX have become quickly adopted as canonic markers of biological sex, while at the same time it has been conceded that biological sex does not produce uniform gender identity. In this chapter I will be looking at some of the components of the biological construction of sex, such as hormones and molecular genetics.

Since the beginning of the discipline of endocrinology, there has been debate about the gendered nature of hormones themselves. The “sex hormones” continue to be referred to as such in clinical practice, largely due to their role in reproduction and development, despite their multiple non-gender-specific regulatory roles. The construction of hormones and genes on one hand shifts the biological locus of sex from chromosomes to a molecular level and on the other hand creates a context-driven medicalization of gender.

Keywords

Gender Identity Female Body Gender Dysphoria Androgen Insensitivity Syndrome Gender Body 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Butler, J. (2004). Undoing gender. New York: Routledge.Google Scholar
  2. 2.
    Fausto-Sterling, A. (2000). Sexing the body. New York: Basic Books, 51–53.Google Scholar
  3. 3.
    Reis, E. (2009). Bodies in doubt. Baltimore: John Hopkins Press.Google Scholar
  4. 4.
    Laqueur, T. (1990). Making sex: Body and gender from the Greeks to Freud. Cambridge, MA: Harvard University Press, 161.Google Scholar
  5. 5.
    Painter, T. S. (1923). Studies in mammalian spermatogenesis II. The spermatogenesis of man. Journal of Experimental Zoology, 37, 291–336.CrossRefGoogle Scholar
  6. 6.
    Miller, F. A. (2006, September). ‘Your true and proper gender’: The Barr body as a good enough science of sex. Studies in History and Philosophy of Biological and Biomedical Science, 37, 459–483.CrossRefGoogle Scholar
  7. 7.
    Reis, E. (2009). Epilogue divergence or didorder? The politicis of naming intersex (p. 153).Google Scholar
  8. 8.
    Roberts, C. (2007). Messengers of sex. New York: Cambridge University Press, 33.CrossRefGoogle Scholar
  9. 9.
    Thomas, D. (2006). Wolffian and Mullerian structures. Rome: Promoarch Eventi.Google Scholar
  10. 10.
    Butler, J. (1990). Gender trouble feminism and the subversion of identity. London: Routledge.Google Scholar
  11. 11.
    Holme, I. (2007). Genetic sex: “A symbolic struggle against reality?”. University of Exeter Doctoral thesis.Google Scholar
  12. 12.
    Nef, V. (2009). Complementary pathways in mammalian female sex determination. Journal of Biology, 8, 74.PubMedCrossRefGoogle Scholar
  13. 13.
    Biason-Lauber, A. (2006). Role of WNT4 gene in gonadal differentiation. Rome: Promoarch Eventi.Google Scholar
  14. 14.
    Jabolonka, E., & Lamb, M. (2005). Evolution in four dimensions. Cambridge, MA: MIT Press, 28–113.Google Scholar
  15. 15.
    Dreger, A. D. (1999). Intersex in the age of ethics. Hagerstown: University Publishing Group, 42.Google Scholar
  16. 16.
    Caffaratto, M. T. (1963). L’ermafroditismo umano. Storia-clinica-medicina legale. Roma: Minerva Medica, 32.Google Scholar
  17. 17.
    Temple, R. (2007). The genius of China: 3,000 years of science, discovery, and invention. Rochester: Inner Traditions.Google Scholar
  18. 18.
    Sengoopta, C. (2006). The most secret quintessence of life: Sex, glands, and hormones, 1850–1950. Chicago: University of Chicago Press, 33.Google Scholar
  19. 19.
    Sengoopta, C. (2000). The modern ovary: Constructions, meanings, uses. History of Science, xxxviii, 425.Google Scholar
  20. 20.
    Oudshoorn, N. (1994). Beyond the natural body. London: Routledge, 18–108.CrossRefGoogle Scholar
  21. 21.
    Rechtor, J. (1997). ‘The Glands of Destiny’: A history of popular, medical, and scientific views of the sex hormones in the 1920s America. Doctoral thesis, University of California, Berkeley.Google Scholar
  22. 22.
    Dreger, A. D. (1998). Hermaphrodites and the medical invention of sex. Cambridge, MA: Harvard University Press.Google Scholar
  23. 23.
    Callard, P. R. (1978). Conversion of androgen to estrogen and other steroids in the vertebrate brain. American Zoologist, 18(3), 511–523.Google Scholar
  24. 24.
    Panzer, et al. (2006). Original research—Women’s sexual dysfunction: Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: A retrospective study in women with sexual dysfunction. The Journal of Sexual Medicine, 3, 104–113.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2013

Authors and Affiliations

  1. 1.Department of PhilosophyUniversity of BolognaBolognaItaly

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