Abstract
Superficial thrombophlebitis offers an array of presentations. Yet despite the knowledge that has emerged over the past 20 years, the curricula in medical schools and residencies fail to acknowledge STP as anything more than a self-limiting disease. The gap in venous education in the USA leads many unknowing providers to prescribe a recipe for thrombus extension, based upon established yet inaccurate dogma associated with STP. Although clinical trials are emerging, there is far more to be learned about this topic. This chapter discusses the latest in peer-reviewed literature, enabling the reader to optimize outcomes through minimizing the risk of complications related to this common venous condition of the lower extremity.
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Hingorani A, Ascher E. Superficial venous thrombophlebitis. In: Gloviczki P, editor in chief. Handbook of venous disorders. 3rd ed. London: Hodder Arnold; 2009. p. 314–9.
Hill S, Hancock D, Webb T. Thrombophlebitis of the great saphenous vein – recommendations for treatment. Phlebology. 2008;23:35–9.
DeMaeseneer M. Letter to editor RE: treatment of superficial thrombophlebitis of the great saphenous vein. Phlebology. 2008;23:299.
Quenet S, Laporte S, Decousus H, et al. Factors predictive of venous thrombotic complications in patients with isolated superficial vein thrombosis. J Vasc Surg. 2003;38:944–9.
Feied C. Venous thrombosis and pulmonary embolism. In: Marx J, Hockberger R, Walls R, editors. Rosen’s emergency medicine: concepts and clinical practice. 5th ed. St. Louis: Mosby; 2002. p. 1211–2.
DeGowin R. Thrombophlebitis. DeGowin & DeGowin’s bedside diagnostic examination. 5th ed. New York: Macmillan Publishing Company; 1987. p. 441–5.
Allen E, Barker N, Hines E, et al. Peripheral vascular diseases. Philadelphia: WB Saunders Company; 1946. p. 636–8.
DePalma R, Johnson G. Superficial thrombophlebitis: diagnosis and management. In: Rutherford R, editor. Vascular surgery, vol. 143. 5th ed. Philadelphia: W.B. Saunders Company; 2000. p. 1979–81.
Decousus H, Leizorovicz A. Superficial thrombophlebitis of the legs: still a lot to learn. J Thromb Haemost. 2005;3:1149–51.
Sobreira M, Maffei F, Yoshida W, et al. Prevalence of deep vein thrombosis and pulmonary embolism in superficial thrombophlebitis of the lower limbs: prospective study of 60 cases. Int Angiol. 2009;28:400–8.
Conant E, Wilkes A, Mendelson E, Feig S. Superficial thrombophlebitis of the breast (Mondor’s disease): mammographic findings. AJR Am J Roentgenol. 1993;160:1201–3.
Coon W, Willis P, Keller J. Venous thromboembolism and other venous disease in the Tecumseh Community Health Study. Circulation. 1973;48:839–46.
DeWeese MS. Nonoperative management of acute superficial thrombophlebitis and deep femoral venous thrombosis. In: Ernst CB, Stanley JC, editors. Current therapy in vascular surgery. Philadelphia: BC Decker; 1991. p. 952–60.
Lutter K, Kerr T, Roedersheimer R, et al. Superficial thrombophlebitis diagnosed by duplex scanning. Surgery. 1991;110:42–6.
Skillman JJ, Kent KC, Porter DH, Kim D. Simultaneous occurrence of superficial and deep thrombophlebitis in the lower extremity. J Vasc Surg. 1990;11:818–24.
Blättler W, Schwarzenbach B, Largiadér J. Superficial vein thrombophlebitis-serious concern or much ado about little? Vasa. 2008;37(1):31–8.
Cotran R, Kumar V, Robbins S, editors. Robbins pathologic basis of disease. 4th ed. Philadelphia: WB Saunders Company; 1989.
Chengelis D, Bendick P, Glover J, et al. Progression of superficial venous thrombosis to deep vein thrombosis. J Vasc Surg. 1996;24:745–9.
Hanson J, Ascher E, DePippo P, et al. Saphenous vein thrombophlebitis (SVT): a deceptively benign disease. J Vasc Surg. 1998;27:677–80.
Dewar C, Panpher S. Incidence of deep vein thrombosis in patients diagnosed with superficial thrombophlebitis after presenting to an emergency department outpatient deep vein thrombosis service. Emerg Med J. 2010;27:758–61.
Kakkos S, Lampropoulos G, Papadoulos S, et al. Seasonal variation in the incidence of superficial thrombophlebitis. Thromb Res. 2010;126(2):98–102.
Blumenberg R, Barton E, Gelfand M, et al. Occult deep vein thrombosis complicating superficial thrombophlebitis. J Vasc Surg. 1998;27:338–43.
Sullivan V, Denk P, Sonnad S, et al. Ligation versus anticoagulation: treatment of above-knee superficial thrombophlebitis not involving the deep venous system. J Am Coll Surg. 2001;193(5):556–62.
Verlato F, Zucchetta P, Prandoni P, et al. An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh. J Vasc Surg. 1999;30:1113–5.
Leon L, Giannoukas AD, Dodd D, et al. Clinical significance of superficial vein thrombosis. Eur J Vasc Endovasc Surg. 2005;29:10–7.
Olubaniyi BO, Kumar S, Dimitri S, et al. Superficial thrombophlebitis of lower limb veins – far from a benign condition. Br J Surg. 2009;96(S1):1–15.
Decousus H, Epinat M, Guillot K, et al. Superficial vein thrombosis: risk factors, diagnosis, and treatment. Curr Opin Pulm Med. 2003;9:393–7.
Cesarone M, Belcaro G, Agus G, et al. Management of superficial vein thrombosis and thrombophlebitis: status and expert opinion document. Angiology. 2007;58(1):7–15.
Coleridge-Smith P, Labropoulos N, Partsch H, et al. Duplex ultrasound investigation of the veins in chronic venous disease of the lower limbs – UIP consensus document. Part I: basic principles. Phlebology. 2006;21:158–67.
Ascer E, Lorenson E, Pollina R, Gennaro M. Preliminary results of a nonoperative approach to saphenofemoral junction thrombophlebitis. J Vasc Surg. 1995;22:616–21.
Wasserman D, Bonner K, et al. Duplex surveillance of superficial thrombophlebitis. Vasc Surg. 1997;31(4):427–31.
Chopra A. Thrombophlebitis and occlusive arterial disease. In: Tintinalli J, Kelen G, Stapczynski J, editors. Emergency medicine a comprehensive guide. 6th ed. New York: McGraw-Hill; 2004. p. 409–10.
Comerata A. Comment on duplex surveillance of superficial thrombophlebitis. Vasc Surg. 1997;31(4):430–1.
Schönauer V, Kyrle P, Weltermann A, et al. Superficial thrombophlebitis and risk for recurrent venous thromboembolism. J Vasc Surg. 2003;37:834–8.
Wilmanns C, Casey A, Schinzel H, Walter P. Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. Phlebology. 2011;26:135–9.
Nutescu E, Michaud J, Caprini J. Evaluation of hypercoagulable states and molecular markers of acute venous thrombosis. In: Gloviczki P, editor in chief. Handbook of venous disorders. 3rd ed. London: Hodder Arnold; 2009. p. 113–28.
Junger M, Diehm C, Storiko H, et al. Mobilization versus immobilization in the treatment of acute proximal deep vein thrombosis: a prospective, randomized, open, multicenter trial. Curr Med Res Opin. 2006;22(3):593–602.
Partsch H, Blattler W. Compression and walking versus bed rest in the treatment of proximal deep venous thrombosis with low molecular weight heparin. J Vasc Surg. 2000;32:861.
Ramelet A. Compression therapy. Dermatol Surg. 2002;28:6–10.
Decousus H, Quere I, Presles E, et al. Superficial venous thrombosis and venous thromboembolism. Ann Intern Med. 2010;152:218–24.
Decousus H, Prandoni P, Mismetti P, et al. Fondaparinux for the treatment of superficial-vein thrombosis in the legs. N Engl J Med. 2010;363:1222–32.
Decousus H, Bregeault M, Darmon J, et al. A pilot randomized double-blind comparison of a low-molecular weight heparin, a nonsteroidal anti-inflammatory agent, and placebo in the treatment of superficial vein thrombosis. Arch Intern Med. 2003;163:1657–63.
Wichers I, DiNisio M, Buller H, Middeldorp S. Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review. Haematologica. 2005;90:672–7.
Di Nisio M, Wichers I, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev. 2007;(2):CD004982.
Kearon C, Kahn S, Agnelli G, et al. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence based clinical practice guidelines (8th Edition). Chest. 2008;133:454S–545.
Bauer K. Duration of anticoagulation: applying the guidelines and beyond. Hematology Am Soc Hematol Educ Program. 2010;2010:210–5.
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Schul, M.W. (2014). Superficial Venous Thrombophlebitis. In: Mowatt-Larssen, E., Desai, S., Dua, A., Shortell, C. (eds) Phlebology, Vein Surgery and Ultrasonography. Springer, Cham. https://doi.org/10.1007/978-3-319-01812-6_19
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