Abstract
Definition: A high-grade malignant neoplasm characterized by tumor cells with diffuse pleomorphism in the absence of a specific line of differentiation.
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Bielack SS, Schroeders A, Fuchs N, Bacci G, Bauer HC, Mapeli S, Tomeno B, Winkler K (1999) Malignant fibrous histiocytoma of bone: a retrospective EMSOS study of 125 cases. European Musculo-Skeletal Oncology Society. Acta Orthop Scand 70(4):353–360
Hoekstra HJ, Ham SJ, van der Graaf WT, Kamps WA, Molenaar WM, Schraffordt KH (1998) Malignant fibrous histiocytoma of bone: a clinicopathologic study of 81 patients. Cancer 82(5):993–994
Koplas MC, Lefkowitz RA, Bauer TW, Joyce MJ, Ilaslan H, Landa J, Sundaram M (2010) Imaging findings, prevalence and outcome of de novo and secondary malignant fibrous histiocytoma of bone. Skeletal Radiol 39(8):791–798
Niini T, Lahti L, Michelacci F, Ninomiya S, Hattinger CM, Guled M, Böhling T, Picci P, Serra M, Knuutila S (2011) Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone. Genes Chromosomes Cancer 50:291–306
Tarkkanen M, Larramendy ML, Böhling T, Serra M, Hattinger CM, Kivioja A, Elomaa I, Picci P, Knuutila S (2006) Malignant fibrous histiocytoma of bone: analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry. Eur J Cancer 42(8):1172–1180
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Picci, P. (2014). Undifferentiated Pleomorphic Sarcoma (UPS). In: Picci, P., Manfrini, M., Fabbri, N., Gambarotti, M., Vanel, D. (eds) Atlas of Musculoskeletal Tumors and Tumorlike Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-01748-8_45
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DOI: https://doi.org/10.1007/978-3-319-01748-8_45
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