Abstract
Epidemiology: It is the most frequent primary malignant tumor of bone, excluding myeloma, considered a systemic neoplasm. Its incidence is of 2–3 cases/million/year (only 0.2 % of all malignancies). Males are preferred (1.5:1). Most cases occur between 10 and 20 years of age. Older patients are usually secondary to radiation, Paget, chondrosarcoma, other primary bone tumors, or idiopathic.
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Picci, P. (2014). Classic Osteosarcoma. In: Picci, P., Manfrini, M., Fabbri, N., Gambarotti, M., Vanel, D. (eds) Atlas of Musculoskeletal Tumors and Tumorlike Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-01748-8_34
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DOI: https://doi.org/10.1007/978-3-319-01748-8_34
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