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Swelling Behaviour of Functionalized Hydrogels for Application in Chemical Sensors

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Intelligent Hydrogels

Part of the book series: Progress in Colloid and Polymer Science ((PROGCOLLOID,volume 140))

Abstract

Thin films of metabolite-specific biocompatible hydrogels were combined with microfabricated piezoresistive pressure transducers to obtain chemomechanical sensors that can serve as selective biochemical sensors for a continuous monitoring of metabolites. The gel swelling pressure has been monitored in simulated physiological solutions by means of the output signal of piezoresistive sensors. Gel response time and accuracy with which hydrogels can track gradual changes in glucose, fructose, pH and CO2, respectively, were estimated. A significant reduction of the sensor response time has been achieved due to hygroscopic fibres incorporated in the hydrogel layer.

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Acknowledgments

M. N. Avula, F. Solzbacher, P. Tathireddy, S. H. Cho, and J. J. Magda are acknowledged for the help with the parylene C coating as well as for the preparation of pre-gel solutions. The authors gratefully acknowledge support of this work from the Deutsche Forschungsgemeinschaft (SPP 1259, grant Ge 779/14-3).

Author information

Authors and Affiliations

  1. Solid-State Electronics Lab, Technische Universität Dresden, Helmholtzstr. 10, 01069, Dresden, Germany

    Margarita Guenther & Gerald Gerlach

  2. Institute of Solid Mechanics, Technische Universität Dresden, George-Bähr-Str. 3c, 01062, Dresden, Germany

    Thomas Wallmersperger

  3. Institute for Statics and Dynamics of Aerospace Structures, Universität Stuttgart, Pfaffenwaldring 27, 70569, Stuttgart, Germany

    Karsten Keller

Authors
  1. Margarita Guenther
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  2. Thomas Wallmersperger
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  3. Karsten Keller
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  4. Gerald Gerlach
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Corresponding author

Correspondence to Margarita Guenther .

Editor information

Editors and Affiliations

  1. Fakultät Bio- und Chemieingenieurwesen Thermodynamik, Technische Universität Dortmund, Dortmund, Germany

    Gabriele Sadowski

  2. RWTH Aachen LS für Physikalische Chemie II, Aachen, Germany

    Walter Richtering

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© 2013 Springer International Publishing Switzerland

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Guenther, M., Wallmersperger, T., Keller, K., Gerlach, G. (2013). Swelling Behaviour of Functionalized Hydrogels for Application in Chemical Sensors. In: Sadowski, G., Richtering, W. (eds) Intelligent Hydrogels. Progress in Colloid and Polymer Science, vol 140. Springer, Cham. https://doi.org/10.1007/978-3-319-01683-2_20

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