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Adverse Effects of Bisphenol A on Male Reproductive Function

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Book cover Reviews of Environmental Contamination and Toxicology Volume 228

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 228))

Abstract

Infertility is one of the major health problems that affect human sociocultural life. It affects 8–15 % of couples around the world, and about 50 % of infertility cases are attributed to male factors (WHO 1991; Cui 2010; Hamada et al. 2011). Among the factors that cause male infertility are exposures to environmental toxicants (Akingbemi et al. 2004). Bisphenol A ([2,2-bis(4-hydroxyphenyl)propane]: BPA) is among the most prominent of toxic environmental contaminants worldwide. The original synthesis of BPA is attributed to two scientists: Dianin, who is thought to have been the first to design the molecule in 1891, and Zincke, who reportedly synthesized the molecule in 1905 (Huang et al. 2011). Since then, BPA has been widely produced and used as a common ingredient in the manufacture of plastics. Plastics are broadly integrated into today’s lifestyle and make a major contribution to almost all product areas (Olea et al. 1996; Völkel et al. 2011; Hammer et al. 2012). The wide and heavy use of plastics has contributed to BPA having been spread throughout the environment.

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Acknowledgements

This work was funded by the Federation of Indian Chambers of Commerce & Industry (FICCI), the Department of Science and Technology (DST), and Government of India, through CV Raman International Fellowship for African Researchers.

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, 63, Buea, Cameroon

    Faustin Pascal Tsagué Manfo

  2. Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, 605014, India

    Rajamanickam Jubendradass & Premendu Prakash Mathur

  3. Department of Biological Science, Faculty of Science, University of Bamenda, 39, Bambili, Cameroon

    Edouard Akono Nantia

  4. Laboratory of Pharmacology and Toxicology, Department of Biochemistry, Faculty of Science, University of Yaoundé I, 812, Yaoundé, Cameroon

    Paul Fewou Moundipa

  5. KIIT University, Bhubaneshwar, 751024, Odisha, India

    Premendu Prakash Mathur

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  1. Faustin Pascal Tsagué Manfo
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    David M. Whitacre

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Manfo, F.P.T., Jubendradass, R., Nantia, E.A., Moundipa, P.F., Mathur, P.P. (2014). Adverse Effects of Bisphenol A on Male Reproductive Function. In: Whitacre, D. (eds) Reviews of Environmental Contamination and Toxicology Volume 228. Reviews of Environmental Contamination and Toxicology, vol 228. Springer, Cham. https://doi.org/10.1007/978-3-319-01619-1_3

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