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Determination of Benzophenone-3 and its Metabolites in Human Semen by Solid-Phase Extraction and Liquid Chromatography Tandem Mass Spectrometry

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Abstract

The contribution of analytical tools to develop further research on the process of bioaccumulation and toxicity in the male reproductive system of BZ3 and its metabolites is necessary considering the systemic properties that exhibit this type of compounds.

Some content of this chapter has been published in Anal Bioanal Chem (2010) 398:831–843 and presented as poster communication at the 28th international Symposium on Chromatography (ISC) held in Valencia (Spain) in September 2010.

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Notes

  1. 1.

    WHO Laboratory Manual for the Examination and Processing of Human Semen (2010), 5th edn. World Health Organization.

  2. 2.

    ICH validation of analytical procedures methodology: text and methodology Q2(R1), ICH harmonised tripartite guidelines, Adopted November (2005).

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Correspondence to Zacarías León González .

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León González, Z. (2014). Determination of Benzophenone-3 and its Metabolites in Human Semen by Solid-Phase Extraction and Liquid Chromatography Tandem Mass Spectrometry. In: Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-01189-9_5

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