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Antigen Delivery Systems as Oral Adjuvants

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Abstract

Animals, including humans, have evolved a sophisticated mucosal immune system. By understanding mucosal immune activation, we can rationally design adjuvants to elicit a long-lasting protective immune response. In this chapter we will discuss about what is known about mucosal immunity and oral adjuvants. In particular, we will specially focus on polymeric nanoparticles as mucosal adjuvants that have been developed to stimulate lifelong memory for vaccination purposes.

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Authors and Affiliations

  1. Department of Microbiology, University of Navarra, Pamplona, Spain

    Carlos Gamazo PhD

  2. Department of Pharmacy and Pharmaceutical Technology, University of Navarra, Pamplona, Spain

    Juan M. Irache PhD

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  1. Carlos Gamazo PhD
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  1. Institute for Molecular Vaccines, Heidelberg, Germany

    Matthias Giese

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Gamazo, C., Irache, J.M. (2014). Antigen Delivery Systems as Oral Adjuvants. In: Giese, M. (eds) Molecular Vaccines. Springer, Cham. https://doi.org/10.1007/978-3-319-00978-0_12

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