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Protein Folding: An Introduction

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Protein Folding

Part of the book series: SpringerBriefs in Molecular Science ((BRIEFSPROTEIN))

Abstract

We have come a long way since coining of the term protein and the early findings that proteins are charged macromolecules composed of strings of amino acids linked by peptide bonds. Today, structural biologists have technologies that allow in many cases to achieve an atomic-level understanding of protein structure, dynamics and folding; protein physics approaches have made substantial contributions to understanding the intricacies of folding mechanisms and its energetics; biochemists have developed conceptual frameworks to relate protein structure with biological functions. Yet, despite the efforts of a vibrant community of protein scientists, a lot of questions remain to be answered in the field of protein structure and folding.

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  1. Department of Chemistry and Biochemistry, Faculty of Sciences, Biosystems & Integrative Sciences Institute, University of Lisbon, Lisbon, Portugal

    Cláudio M. Gomes

  2. Department of Physics, Faculty of Sciences, Biosystems & Integrative Sciences Institute, University of Lisbon, Lisbon, Portugal

    Patrícia F. N. Faísca

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Gomes, C.M., Faísca, P.F.N. (2019). Protein Folding: An Introduction. In: Protein Folding. SpringerBriefs in Molecular Science(). Springer, Cham. https://doi.org/10.1007/978-3-319-00882-0_1

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