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Zinc(II) Phthalocyanine-Polyamine Conjugates as Efficient Photosensitizers for Photodynamic Therapy

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Towards Dual and Targeted Cancer Therapy with Novel Phthalocyanine-based Photosensitizers

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Abstract

One of the major imperfections of photodynamic therapy (PDT) is the nonselective delivery of photosensitizers to both targeted tumor and healthy cells. It frequently leads to necrosis of surrounding healthy tissues along with a cutaneous photosensitivity that may last for several weeks after treatment. As a result, targeted delivery of photosensitizers to cancer cells appears to be a viable means to circumvent these problems.

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Authors and Affiliations

  1. Department of Chemistry, The Chinese University of Hong Kong, Shatin, 852, People’s Republic of China

    Janet T. F. Lau

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  1. Janet T. F. Lau
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Correspondence to Janet T. F. Lau .

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Lau, J.T.F. (2013). Zinc(II) Phthalocyanine-Polyamine Conjugates as Efficient Photosensitizers for Photodynamic Therapy. In: Towards Dual and Targeted Cancer Therapy with Novel Phthalocyanine-based Photosensitizers. Springer Theses. Springer, Heidelberg. https://doi.org/10.1007/978-3-319-00708-3_3

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