Abstract
According to recent studies and with those developed in this work we can say that the biomaterials chitosan and poly vinyl alcohol (PVAL) have excellent compatibility and have together formed a homogeneous mixture. The blend of chitosan and PVAL subjected to electron beam radiation at a dose 25 kGy had better mechanical properties and great ability to swell, the change in properties occurred due to crosslinking in its structure. During radiation, the transfer occurs primarily of energy that leads to excitation of electrons, and then followed by physical–chemical processes like the formation of free radicals and finally the recombination of radicals forming crosslinks. The degree of crosslinking is proportional to the absorbed dose and is independent of radiation intensity. In our study, membranes of chitosan and poly vinyl alcohol after a radiation dose of 25 kGy achieved better hygroscopic properties, greater resistance to temperature fluctuations and mechanical properties formidable. These results were obtained in tests: mechanical analysis of stress and strain of the material to characterize the membrane, swelling as the water absorption and thermal analysis to verify the strength of the material with temperature and thus allowing analyzing the degradation of the biomaterial.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Rinaudo, M.: Chitin and chitosan: properties and applications. Prog. Polym. Sci. 31, 603–632 (2006)
Goosen, M.F.A.: Applications of Chitin and Chitosan. Technomic, Basel (1997)
Terence, M.C., Miranda, L.F., Faldini, S.B., Castro, P.J.: Study of chitosan addition in the PVP/PVAL polymeric blend. Adv. Sci. Tech. 76, 190–194 (2010)
Rodrigues, I.R.: Síntese e caracterização de redes poliméricas a base de quitosana com PVP e PVA para aplicação na liberação controlada de fármacos. Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Dissertação de mestrado (2006)
Terence, M.C., Faldini, S.B., Miranda, L.F., Munhoz A.H., Jr.,, Castro, P.J.: Preparation and characterization of a polymeric blend of PVP/PVAL for use in drug delivery system. J. Biomed. Nanotech. 7, 446–449 (2011)
Peppas, N.A., Bures, P., Leobandung, W., Ichikawa, H.: Hydrogels in pharmaceutical formulations. Eur. J. Pharm. Biopharm. 50, 27–46 (2000)
Barros, F.C.F., Carvalho, T.V., Cavalcante, R.M., Dias, F.S., Nascimento, R.F., Queiroz, D.C., Vasconcellos, L.C.G.: Produção e caracterização de esfera de quitosana modificada quimicamente. Rev Iberoamer Polím 7, 232–246 (2006)
Santos, J.E., Soares, J.P., Dockal, E.R., et al.: Caracterização de quitosanas comerciais de diferentes origens de polímeros. Polímeros: Ciência e Tecnologia 13: 242–249 (2003)
Terence, M.C.: Obtenção de um sistema de liberação controlada de drogas a partir do PVAL irradiado com radiação gama. Tese de Doutorado, IPEN, São Paulo (2002)
Rosa, D.S.: Modificação de polietileno de baixa densidade, polipropileno isotático e suas blendas, por radiação gama. Universidade Estadual de Campinas, Campinas, Tese de Mestrado (1991)
Wan Y, Creber KAM, Peppley B, Tam Bui V (2003) Synthesis, characterization and ionic conductive properties of phosphorylated chitosan membranes. Macromol Chem Phys 204: 850–858
Callister W.D. Jr.,: Material Science and Engineering: An Introduction. Wiley, New York (2004)
Felisberti, M.I.: Apostila de caracterização de blendas poliméricas através de análise térmica e termomecânica. Universidade Estadual de Campinas, Campinas (1998)
Miranda, L.F.: Estudo de parâmetros de processo para a síntese de membranas hidrofílicas a base de poli(N-vinil-2-pirrolidona. Tese de Doutorado, IPEN, São Paulo (1999)
José, N.M., Souza, C.M.L., Felisberti, M.I., Yoshida, I.V.P.: Síntese de redes a base de PDMS e reticulantes dendríticos. Anais do Congresso Brasileiro de Engenharia e Ciência dos Materiais, São Pedro (2000)
Canevarolo S.V. Jr.,: Análise térmica dinâmico-mecânica. Canevarolo SV Jr Técnicas de caracterização de polímeros, Artliber, São Carlos (2004)
Oliveira, MJA., Rodrigues, KMS., Oliveira, TF., Parra, DF., Lugão, AB.: Hidrogéis de poli(álcool vinílico)/poli(n-2-pirrolidona) para liberação de fármaco. In: 9 Congresso Brasileiro de Polímeros, Campina Grande (2007)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Terence, M.C., de Souza, J.R., Faldini, S.B., Miranda, L.F., Pereira, N.C. (2013). Chitosan and Poly (Vinyl Alcohol) Blends Modified by Radiation. In: Ochsner, A., Altenbach, H. (eds) Advances in Bio-Mechanical Systems and Materials. Advanced Structured Materials, vol 40. Springer, Cham. https://doi.org/10.1007/978-3-319-00479-2_10
Download citation
DOI: https://doi.org/10.1007/978-3-319-00479-2_10
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-00478-5
Online ISBN: 978-3-319-00479-2
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)