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Resin Glycosides from the Morning Glory Family

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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 92

Abstract

Resin glycosides are part of a very extensive family of secondary metabolites known as glycolipids or lipo-oligosaccharides and are constituents of complex resins (glycoresins) (1) unique to the morning glory family, Convolvulaceae (2). These active principles are responsible for the drastic purgative action of all the important Convolvulaceous species used in traditional medicine throughout the world since ancient times. Several commercial purgative crude drugs can be prepared from the roots of different species of Mexican morning glories. Their incorporation as therapeutic agents in Europe is an outstanding example of the assimilation of botanical drugs from the Americas as substitutes for traditional Old World remedies (3). Even though phytochemical investigations on the constituents of these drugs were initiated during the second half of the nineteenth century, the structure of their active ingredients still remains poorly known for some examples of these purgative roots. During the last two decades, the higher resolution capabilities of modern analytical isolation techniques used in conjunction with powerful spectroscopic methods have facilitated the elucidation of the active principles of these relevant herbal products.

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Acknowledgements

The corresponding author would like to express his gratitude to both the “Consejo Nacional de Ciencia y Tecnología” and the “Dirección General de Asuntos del Personal Académico” (UNAM) for their support of the chemical investigations of the morning glories used in Mexican traditional medicine through a series of grants over the past decade.

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Authors and Affiliations

  1. Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, DF, México

    Rogelio Pereda-Miranda, Daniel Rosas-Ramírez & Jhon Castañeda-Gómez

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  1. Rogelio Pereda-Miranda
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  2. Daniel Rosas-Ramírez
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  3. Jhon Castañeda-Gómez
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Correspondence to Rogelio Pereda-Miranda .

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  1. College of Pharmacy, Ohio State University, West 12th Ave. 500, Columbus, 43210, USA

    A. Douglas Kinghorn

  2. Inst. Organische Chemie, Universität Linz, Altenbergerstr. 69, Linz, 4040, Austria

    Heinz Falk

  3. Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka, 812-8582, Japan

    Junichi Kobayashi

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Pereda-Miranda, R., Rosas-Ramírez, D., Castañeda-Gómez, J. (2010). Resin Glycosides from the Morning Glory Family. In: Kinghorn, A., Falk, H., Kobayashi, J. (eds) Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 92. Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, vol 92. Springer, Vienna. https://doi.org/10.1007/978-3-211-99661-4_2

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