Abstract
In addition to asparagine-linked oligosaccharides (N-glycans), many glycoproteins bear serine-linked or threonine- linked oligosaccharides (O-glycans). The O-glycans considered here have as the core sugar N-acetylgalactosamine α-linked to the hydroxyl group of serine or threonine. Other O-glycans have xylose, fucose, or N-acetylglucosamine as the core sugar. Mucin glycoproteins that cover the digestive, respiratory, and genitourinary tract possess a high number of O-glycans that bind water and ions, serve as lubricants, and provide a defence against microbial invaders.
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Pavelka, M., Roth, J. (2010). Topography of Biosynthesis of Serine/Threonine-Linked Oligosaccharides. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_33
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DOI: https://doi.org/10.1007/978-3-211-99390-3_33
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-99389-7
Online ISBN: 978-3-211-99390-3
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