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Nuclear Pore Complexes: Structural Changes as Monitored by Time-Lapse Atomic Force Microscopy

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Abstract

Atomic force microscopy is a unique imaging technique that allows high resolution studies of biological macromolecules in a native state under quasi-physiological conditions in an aqueous environment. In addition to static structural analysis, dynamic structural analysis by time lapse imaging in response to stimuli as well as of growth and growth kinetics of macromolecules has been achieved. The examples shown here concern the structure of native nuclear pore complexes and structural changes in response to calcium.

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Authors and Affiliations

  1. Center for Anatomy and Cell Biology, Department of Cell Biology and Ultrastructure Research, Medical University of Vienna, Vienna, Austria

    o. Univ. Prof. Dr. med. Margit Pavelka

  2. Yonsei University Graduate School, World Class University Program, Department of Biomedical Science, Yonsei University, Seoul, Korea

    Prof. Dr. med. Dr. sc. Dr. h. c. Jürgen Roth

Authors
  1. o. Univ. Prof. Dr. med. Margit Pavelka
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  2. Prof. Dr. med. Dr. sc. Dr. h. c. Jürgen Roth
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© 2010 Springer-Verlag/Wien

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Pavelka, M., Roth, J. (2010). Nuclear Pore Complexes: Structural Changes as Monitored by Time-Lapse Atomic Force Microscopy. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_10

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