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Haut und Hautersatz, Tissue Engineering

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Verbrennungen

Zusammenfassung

Die Haut ist nicht nur das größte Organ des menschlichen Körpers, sondern auch die primäre Immunbarriere. Daher stellt der großflächige Verlust der Haut durch thermische Traumata nicht nur eine lebensbedrohliche Situation für die Betroffenen, sondern durch die Notwendigkeit des Hautersatzes noch immer eine ernsthafte Herausforderung in der Plastischen und Verbrennungschirurgie dar. Die Entwicklung und ständige Verbesserung innovativer Methoden der Hautexpansion sowie des Tissue Engineering lassen heute Verbrannte mit mehr als 80% verbrannter Körperoberfläche überleben. Zwar hat sich die Applikation gezüchteter Epidermis und zusammengesetzter kultivierter Hautkonstrukte als lebensrettende Maßnahme etabliert — jedoch ist die Indikationsstellung, ab welcher diese Technologie zum Einsatz kommt, immer enger geworden.

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Horch, R.E., Kopp, J. (2009). Haut und Hautersatz, Tissue Engineering. In: Kamolz, LP., Herndon, D.N., Jeschke, M.G. (eds) Verbrennungen. Springer, Vienna. https://doi.org/10.1007/978-3-211-79896-6_12

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