Abstract
Abatacept (Orencia®) is an injectable, synthetic (man-made) soluble fusion protein that consists of the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) linked to the modified Fc portion of human immunoglobulin G1 (IgG1). Abatacept is produced by recombinant DNA technology in a mammalian cell expression system.
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© 2009 Springer-Verlag/Wien
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(2009). Abatacept. In: Rovenský, J., Payer, J. (eds) Dictionary of Rheumatology. Springer, Vienna. https://doi.org/10.1007/978-3-211-79280-3_5
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DOI: https://doi.org/10.1007/978-3-211-79280-3_5
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-68584-6
Online ISBN: 978-3-211-79280-3
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