Zusammenfassung
Unter dem Begriff „Antidepressiva“ (der ältere Begriff „Thymoleptika“ wird heute nicht mehr verwendet) wird eine chemisch und pharmakologisch heterogene Klasse von Neuro-Psychopharmaka zusammengefasst, die ursprünglich vorwiegend bei Patienten mit depressiven Symptomen eingesetzt wurde, heute aber eine weit über die depressive Störung hinausgehende therapeutische Anwendung findet. So werden diese Wirkstoffe auch bei Zwangs-, generalisierten Angst-, Panik-, phobischen und Ess-Störungen, mutistischen Verhaltensweisen und ADHS mit gutem klinischen Erfolg eingesetzt. Aufgrund der Na+-Kanal-blockierenden Wirkung der trizyklischen Antidepressiva eignen sich diese auch zur Behandlung neuropathischer Schmerzen. Der Oberbegriff Antidepressiva ist deshalb heute formal gesehen nicht mehr ganz korrekt.
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Taurines, R., Wewetzer, C., Warnke, A., Gerlach, M. (2009). Antidepressiva. In: Gerlach, M., Warnke, A., Mehler-Wex, C., Walitza, S., Wewetzer, C. (eds) Neuro-Psychopharmaka im Kindes- und Jugendalter. Springer, Vienna. https://doi.org/10.1007/978-3-211-79275-9_6
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