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Hypomelanosis of Ito and Related Disorders (Pigmentary Mosaicism)

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Neurocutaneous Disorders Phakomatoses and Hamartoneoplastic Syndromes

Abstract

The term hypomelanosis of Ito (HI) (OMIM # 300337) encompasses a heterogeneous group of disorders characterised by hypopigmented whorls and streaks following the lines of Blaschko (Taibjee et al. 2004). Blaschko’s lines represent a non-random developmental system of linear and/or whorled streaks first described in 1901 (Blaschko 1901) as a constant pattern of cutaneous markings characterising the distribution of various linear and segmental skin disorders (Bologna et al. 1994; Happle 1985, 1993).

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Authors and Affiliations

  1. Paediatric Neurology Service, University Hospital La Paz, University of Madrid, Paseo de la Castellana, 261, 28046, Madrid, Spain

    Ignacio Pascual-Castroviejo MD

  2. National Research Council, Catania, and Department of Paediatrics, University of Catania, Institute of Neurological Science, Viale R. Margherita, 6, 95125, Catania, Italy

    Martino Ruggieri MD, PhD

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  1. Ignacio Pascual-Castroviejo MD
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Editors and Affiliations

  1. Institute of Neurological Science, National Research Council, Catania, Italy

    Martino Ruggieri

  2. University Hospital La Paz, Madrid, Spain

    Ignacio Pascual-Castroviejo

  3. Institute of Neurosurgery, Catholic University of the Sacred Heart, Rome, Italy

    Concezio Di Rocco

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Pascual-Castroviejo, I., Ruggieri, M. (2008). Hypomelanosis of Ito and Related Disorders (Pigmentary Mosaicism). In: Ruggieri, M., Pascual-Castroviejo, I., Di Rocco, C. (eds) Neurocutaneous Disorders Phakomatoses and Hamartoneoplastic Syndromes. Springer, Vienna. https://doi.org/10.1007/978-3-211-69500-5_16

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