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Endometriumkarzinom

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Chirurgische Onkologie
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Das Endometriumkarzinom ist mit einer Inzidenz von 24,7/100 000 Frauen pro Jahr die häufigste maligne Erkrankung des inneren Genitale. Das mittlere Erkrankungsalter liegt bei 68 Jahren, der Altersgipfel zwischen 65 und 70 Jahren. Seit 1988 wird das Endometriumkarzinom entsprechend dem intraoperativen Befund eingeteilt (Tabelle 27.3.1).

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Literatur

  • ACOG Practice Bulletin (2005) Clinical management guidelines for obstetrician-gynecologists. Management of endometrial cancer. Obstet Gynecol 106: 413–424

    Google Scholar 

  • AGO www.awmf.de LL Endometrium-Ca Altintas A, Cosar E, Vardar MA, Demir C, Tuncer I (1999) Intraoperative assessment of depth of myometrial invasion in endometrial carcinoma. Eur J Gynaecol Oncol 20: 329–331

    PubMed  CAS  Google Scholar 

  • Amant F, Moerman P, Neven P, Timmermann D, Van Limbergen E, Vergote I (2005) Endometrial cancer. Lancet 366: 491–505

    Article  PubMed  Google Scholar 

  • Ayhan A, Taskiran C, Celik C, Yuce K (2004) The long-term survival of women with surgical stage II endometrioid type endometrial cancer. Gynecol Oncol 93: 9–13

    Article  PubMed  Google Scholar 

  • Blake P, Lodge N, A’Hern RP (2000) An audit of outcome of adjuvant post-operative radiotherapy for 52 women with stage II carcinoma of the endometrium. Br J Radiol 73: 987–993

    PubMed  CAS  Google Scholar 

  • Craesman NT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Helter PB (1987) Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study. Cancer 60: 2035–2041

    Article  Google Scholar 

  • Emons G, Fleckenstein G, Hinney B, Huschmand A, Heyl W (2000) Hormonal interactions in endometrial cancer. Endocr Rel Cancer 7: 227–242

    Article  CAS  Google Scholar 

  • Emons G, Günthert A, Viereck V, Hanf V (2003) Endokrine Therapie des Endometriumkarzinoms und seiner Präkanzerosen.0 Gynäkologe: 36: 86–96

    Google Scholar 

  • Fagotti A, Ferrandina G, Longo R, Mancuso S, Scambia G (2002) Minilaparotomy in early stage endometrial cancer: an alternative to standard and laparoscopic treatment. Gynecol Oncol 86: 177–183

    Article  PubMed  Google Scholar 

  • Faratian D, Stillie A, Busby-Earle RM, Cowie VJ, Monaghan H (2006) A review of the pathology and management of uterine papillary serous carcinoma and correlation with outcome. Int J Gynecol Cancer 16: 972–978

    Article  PubMed  CAS  Google Scholar 

  • Farthing A (2006) Conserving fertility in the management of gynaecological cancers. BJOG 113: 129–134

    Article  PubMed  CAS  Google Scholar 

  • Grund D, Kohler C, Schneider A, Marnitz S (2006) Role of laparoscopy in the treatment of endometrial carcinoma. Gynakol Geburtshilfliche Rundsch 46: 13–24

    Article  PubMed  Google Scholar 

  • Gu M, Shi W, Barakat RR, Thaler HT, Saigo PE (2000) Peritoneal washings in endometrial carcinoma. A study of 298 patients with histopathologic correlation. Acta Cytol 44: 783–789

    PubMed  CAS  Google Scholar 

  • Gupta JK, Chien PF, Voit D, Clark TJ, Khan KS (2002) Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta-analysis. Acta Obstet Gynecol Scand 81: 799–881 (Autor, bitte Seitenzahl überprüfen)

    Article  PubMed  Google Scholar 

  • Hanf V, Günthert AR, Emons G (2003) Endometrial cancer. Onkologie 26: 429–436

    Article  PubMed  CAS  Google Scholar 

  • Horn LC, Riethdorf L, Löning T (1999) Leitfaden für die Präparation uteriner Operationspräparate. Pathologe 20: 9–14

    Article  PubMed  CAS  Google Scholar 

  • Horn LC, Schurrbusch U, Bilek K, Hentschel B, Einenkel J (2004) Risk of progression in complex and atypical endometrial hyperplasia: Clinicopathologic analysis in cases with and without progestogen treatment. Int J Gynecol Cancer 14: 348–353

    Article  PubMed  Google Scholar 

  • Kayikcioglu F, Boran N, Meydanli MM, Tulunay G, Kose FM, Bulbul D (2002) Is frozen section diagnosis a reliable guide in surgical treatment of stage I endometrial carcinoma? Acta Oncol 41: 444–446

    Article  PubMed  Google Scholar 

  • Kilgore LC, Partridge EE, Alvarez RD, Austin JM, Shingleton HM, Noojin F 3rd, Conner W (1995) Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling. Gynecol Oncol 56: 29–33

    Article  PubMed  CAS  Google Scholar 

  • Kir G, Kir M, Cetiner H, Karateke A, Gurbuz A (2004) Diagnostic problems on frozen section examination of myometrial invasion in patients with endometrial carcinoma with special emphasis on the pitfalls of deep adenomyosis with carcinomatous involvement. Eur J Gynaecol Oncol 25: 211–214

    PubMed  CAS  Google Scholar 

  • Kodama J, Seki N, Ojima Y, Nakamura K, Hongo A, Hiramatsu Y (2006) Risk factors for early and late postoperative complications of patients with endometrial cancer. Eur J Obstet Gynecol Reprod Biol 124: 222–226

    Article  PubMed  Google Scholar 

  • Kohler C, Tozzi R, Klemm P, Schneider A (2003) “Schauta sine utero”: technique and results of laparoscopicvaginal radical parametrectomy. Gynecol Oncol 91: 359–368

    Article  PubMed  Google Scholar 

  • Langer RD, Pierce JJ, O’Hanlan KA, Johnson SR, Espeland MA, Trabal JF, Barnabei VM, Merino MJ, Scully RE (1997) Transvaginal ultrasonography compared with endometrial biopsy for the detection of endometrial disease: Postmenopausal estrogen/progestin interventions trial. N Engl J Med 337: 1792–1798

    Article  PubMed  CAS  Google Scholar 

  • Lelle RJ, Morley GW, Peters WA (1994) The role of vaginal hysterectomy in the treatment of endometrial carcinoma. Int J Gynecol Cancer 4: 342–347

    Article  PubMed  Google Scholar 

  • Leminen A, Forss M, Lehtovirta P (1995) Endometrial adenocarcinoma with clinical evidence of cervical involvement: accuracy of diagnostic procedures, clinical course, and prognostic factors. Acta Obstet Gynecol Scand 74: 61–66

    Article  PubMed  CAS  Google Scholar 

  • Lin LL, Grigsby PW, Powell MA, Mutch DG (2005) Definitive radiotherapy in the management of isolated vaginal recurrences of endometrial cancer. Int J Radiat Oncol Biol Phys 63: 500–504

    PubMed  Google Scholar 

  • Lukka H, Chambers A, Fyles A, Thephamongkhol K, Fung-Kee-Fung M, Elit L, Kwon J (2006) Adjuvant radiotherapy in women with stage I endometrial cancer: a systematic review. Gynecol Oncol 102: 361–368

    Article  PubMed  Google Scholar 

  • Mariani A, Webb MJ, Galli L, Podratz KC (2000) Potential therapeutic role of para-aortic lymphadenectomy in node-positive endometrial cancer. Gynecol Oncol 76: 348–356

    Article  PubMed  CAS  Google Scholar 

  • Marino BD, Burke TW, Tornos C, Chuang L, Mitchell MF, Tortolero-Luna G, Morris M, Gershenson DM (1995) Staging laparotomy for endometrial carcinoma: assessment of peritoneal spread. Gynecol Oncol 56: 34–38

    Article  PubMed  CAS  Google Scholar 

  • Marsden DE, Hacker NF (2001) Optimal management of endometrial hyperplasia. Best Pract Res Clin Obstet Gynaecol 15: 393–405

    Article  PubMed  CAS  Google Scholar 

  • McMeekin DS, Lashbrook D, Gold M, Johnson G, Walker JL, Mannel R (2001) Analysis of FIGO Stage IIIc endometrial cancer patients. Gynecol Oncol 81: 273–278

    Article  PubMed  CAS  Google Scholar 

  • National Comprehensive Cancer Network (2006) Uterine cancers. The complete library of NCCN Clinical Practice Guidelines in Oncology. www.nccn.org

    Google Scholar 

  • Neven P, Vergote I (1998) Should tamoxifen users be screened for endometrial lesions? Lancet 351: 155–157

    Article  PubMed  CAS  Google Scholar 

  • Pavelka JC, Ben-Shachar I, Fowler JM, Ramirez NC, Copeland LJ, Eaton LA, Manolitsas TP, Cohn DE (2004) Morbid obesity and endometrial cancer: surgical, clinical, and pathologic outcomes in surgically managed patients. Gynecol Oncol 95: 588–592

    Article  PubMed  Google Scholar 

  • Prat J (2004) Prognostic parameters of endometrial carcinoma. Hum Pathol 35: 649–662

    Article  PubMed  Google Scholar 

  • Ramirez PT, Frumovitz M, Bodurka DC, Sun CC, Levenback C (2004) Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review. Gynecol Oncol 95: 133–138

    Article  PubMed  CAS  Google Scholar 

  • Ramirez PT, Frumovitz M, Wolf JK, Levenback C (2004) Laparoscopic port-site metastases in patients with gynecological malignancies. Int J Gynecol Cancer 14: 1070–1077

    Article  PubMed  CAS  Google Scholar 

  • Sartori E, Gadducci A, Landoni F, Lissoni A, Maggino T, Zola P, Zanagnolo V (2001) Clinical behavior of 203 stage II endometrial cancer cases: the impact of primary surgical approach and of adjuvant radiation therapy. Int J Gynecol Cancer 11: 430–437

    Article  PubMed  CAS  Google Scholar 

  • Sartori E, Laface B, Gadducci A, Maggino T, Zola P, Landoni F, Zanagnolo V (2003) Factors influencing survival in endometrial cancer relapsing patients: a Cooperation Task Force (CTF) study. Int J Gynecol Cancer 13: 458–465

    Article  PubMed  CAS  Google Scholar 

  • Schröcksnadel H, Fuith LC, Hetzel H (1988) Mehrfachkarzinome in der gynäkologischen Onkologie. Geburtsh Frauenheilk 48: 710–714

    Article  PubMed  Google Scholar 

  • Shaeffer DT, Randall ME (2005) Adjuvant radiotherapy in endometrial carcinoma. Oncologist 10: 623–631

    Article  PubMed  Google Scholar 

  • Silverberg SG, Kurman RJ, Nogales F, Mutter GL, Kubik-Huch RA, Tavassoli FA (2003) Tumors of the uterine corpus. Epithelial tumors and related lesions. In: Tavassoli FA, Devilee P (eds) Pathology and genetics of tumours of the breast and female genital organs. World Health Organization Classification of Tumours. IARC, Lyon, pp 217–232

    Google Scholar 

  • Susini T, Massi G, Amunni G, Carriero C, Marchionni M, Taddei G, Scarselli G (2005) Vaginal hysterectomy and abdominal hysterectomy for treatment of endometrial cancer in the elderly. Gynecol Oncol 96: 362–367

    Article  PubMed  Google Scholar 

  • Tozzi R, Malur S, Köhler C, Schneider A (2005) Analysis of morbidity in patients with endometrial cancer: Is there a commitment to offer laparoscopy? Gyn Onc 97: 4–9

    Article  Google Scholar 

  • Tozzi R, Malur S, Köhler C, Schneider A (2005) Laparoscopy versus laparotomy in endometrial cancer: first analysis of survival of a randomized prospective study. J Minim Invasive Gynecol 12: 130–136

    Article  PubMed  Google Scholar 

  • Van den Bosch T, Van Schoubroeck D, Ameye L, De Brabanter J, Van Huffel S, Timmermann D (2003) Ultrasound assessment of endometrial thickness and endometrial polyps in women on hormonal replacement therapy. Am J Obstet Gynecol 188: 1249–1253

    Article  PubMed  Google Scholar 

  • Wang PH, Yen MS, Yuan CC, Chao KC, Ng HT, Lee WL, Chao HT (1997) Port site metastasis after laparoscopic-assisted vaginal hysterectomy for endometrial cancer: possible mechanisms and prevention. Gynecol Oncol 66: 151–155

    Article  PubMed  CAS  Google Scholar 

  • Yokoyama Y, Maruyama H, Sato S, Saito Y (1997) Indispensability of pelvic and paraaortic lymphadenectomy in endometrial cancer. Gynecol Oncol 64: 411–417

    Article  PubMed  CAS  Google Scholar 

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Schneider, A., Marnitz, S. (2008). Endometriumkarzinom. In: Gnant, M., Schlag, P.M. (eds) Chirurgische Onkologie. Springer, Vienna. https://doi.org/10.1007/978-3-211-48613-9_38

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  • DOI: https://doi.org/10.1007/978-3-211-48613-9_38

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-48612-2

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