Skip to main content
SpringerLink
Log in

Lungenmetastasen

  • Chapter
Chirurgische Onkologie

Auszug

Sekundäre Neoplasien der Lunge finden sich im Obduktionsgut von Tumorpatienten in 20 % bis 55 % (Lee, 1983). Hämatogene Lungenmetastasen werden häufig beim Melanom, Osteochondrosarkom, Hypernephrom, Tumoren im Kopf-/Halsbereich als auch beim Rektumkarzinom gefunden. Bei gastrointestinalen Tumoren ist die Lunge meistens das sekundäre Metastasierungsorgan nach der Leber. Allerdings besteht auch bei gastrointestinalen Karzinomen häufig eine lymphogene Tumorzellverschleppung in die Lunge, insbesondere dann, wenn es sich um einen lokal fortgeschrittenen Primärtumor handelt. So findet man eine diffuse Tumorausbreitung im Lymphsystem der Lunge, die Lymphangiosis carcinomatosa, am häufigsten bei primären Karzinomen von Magen, Pankreas, Mamma, Prostata und Ovarien.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Antunes M, Bernardo J, Salete M, Prieto D, Eugenio L, Tavares P (1999) Excision of pulmonary metastases of osteogenic sarcoma of the limbs. Cardio-Thoracic Surgery 15: 592–596

    Article  CAS  Google Scholar 

  • Baaklini WA, Reinoso MA, Gorin AB, Sharafkaneh A, Manian P (2000) Diagnostic yield of fiberoptic bronchoscopy in evaluating solitary pulmonary nodules. Chest 117: 1049–1054

    Article  PubMed  CAS  Google Scholar 

  • Bacci G, Briccoli A, Ferrari S, Saeter G, Donati D, Longhi A et al. (2000) Neoadjuvant chemotherapy for osteosarcoma of the extremities with synchronous lung metastases: treatment with cisplatin, adriamycin and high dose of methotrexate and ifosfamide. Oncol Rep 7(2): 339–346

    PubMed  CAS  Google Scholar 

  • Bacci G, Bertoni F, Longhi A, Ferrari S, Forni C, Biagini R et al. (2003) Neoadjuvant chemotherapy for high-grade central osteosarcoma of the extremity. Histologic response to preoperative chemotherapy correlates with histologic subtype of the tumor. Chirurg 97(12): 3068–3075

    CAS  Google Scholar 

  • Billingsley KG, Burt ME, Jara E, Ginsberg RJ, Woodruff JM, Leung DH et al. (1999) Pulmonary metastases from soft tissue sarcoma: analysis of patterns of diseases and postmetastasis survival. Ann Surg 229(5): 602–610

    Article  PubMed  CAS  Google Scholar 

  • Briccoli A, Ferrari S, Picci P, Mercuri M, Bacci G, Guernelli N (1999) Surgical treatment of lung metastases from osteosarcoma, based on a series of 206 operated cases. Ann Chir 53: 207–214

    PubMed  CAS  Google Scholar 

  • Couraud L, Laurent F, Velly JF, Dorcier J, Zanotti L, Martigne C et al. (1990) Contribution of x-ray computed tomography and MRI to the surgical diagnosis of bronchial cancers. Comparative evaluation of x-ray computed tomography, MRI and thoracotomy in 111 cases. Ann Chir 44: 649–654

    PubMed  CAS  Google Scholar 

  • De Giacomo T, Rendina EA, Venuta F, Ciccone AM, Coloni GF (1999) Thoracoscopic resection of solitary lung metastases from colorectal cancer is a viable therapeutic option. Chest 115: 1441–1443

    Article  PubMed  Google Scholar 

  • Friedel G, Pastorino U, Ginsberg RJ, Goldstraw P, Johnston M, Pass H et al. (2002) Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the International Registry of Lung Metastases. Eur J Cardiothorac Surg 22(3): 335–344

    Article  PubMed  Google Scholar 

  • Girard P, Ducreux M, Baldeyrou P, Rougier P, Le Chevalier T, Bourgaran J et al. (1996) Surgery for lung metastases from colorectal cancer: Analysis of prognostic factors. J Clin Oncol 14: 2047–2053

    PubMed  CAS  Google Scholar 

  • Iizasa T, Suzuki M, Yoshida S, Motohashi S, Yasufuku K, Iyoda A et al. (2006) Prediction of prognosis and surgical indications for pulmonary metastasectomy from colorectal cancer. Ann Thorac Surg 82(1): 254–260

    Article  PubMed  Google Scholar 

  • Jin GY, Lee JM, Lee YC, Han YM (2004) Acute cerebral infarction after radiofrequency ablation of an atypical carcinoid pulmonary tumor. Am J Roentgenol 182(4): 990–992

    Google Scholar 

  • Kandioler D, Kroemer E, Tuechler H, End A, Mueller MR, Wolner E et al. (1998) Long-term results after repeated surgical removal of pulmonary metastases. Ann Thorac Surg 65: 909–912

    Article  PubMed  CAS  Google Scholar 

  • Khan JH, McElhinney J, Rahman S, George TI, Clark OH, Merrick SH (1998) Pulmonary metastases of endocrine origin. Chest 114: 526–534

    Article  PubMed  CAS  Google Scholar 

  • Kolodziejski L, Goralczyk J, Dyczek S, Duda K, Nabialek T (1999) The role of surgery in lung metastases. Eur J Surg Oncol 25: 410–417

    Article  Google Scholar 

  • Landreneau RJ, Mack MJ, Hazelrigg SR, Naunheim KS, Keenan RJ, Ferson PF (1995) The role of video-assisted thoracic surgery in thoracic oncological practice [see comments]. Cancer Invest 13: 526–539

    Article  PubMed  CAS  Google Scholar 

  • Laurent F, Latrabe V, Vergier B, Montaudon M, Dubrez J (2000) CT-guided transthoracic needle biopsy of pulmonary nodules smaller than 20 mm: results with an automated 20-gauge coaxial cutting needle. Clin Radiol 55: 281–287

    Article  PubMed  CAS  Google Scholar 

  • Lee Y (1983) Breast carcinoma:pattern of metastases at autopsy. J Surg Oncol 23: 175–180

    Article  PubMed  CAS  Google Scholar 

  • Lin JC, Wiechmann RJ, Szwerc MF, Hazelrigg SR, Ferson PF, Naunheim K et al. (1999) Diagnostic and therapeutic video-assisted thoracic surgery resection of pulmonary metastases. Surgery 126: 636–642

    PubMed  CAS  Google Scholar 

  • Loehe F, Kobinger S, Hatz RA, Helmberger T, Loehrs U, Fuerst H (2001) Value of systematic mediastinal lymph node dissection during pulmonary metastasectomy. Ann Thorac Surg 72(1): 225–229

    Article  PubMed  CAS  Google Scholar 

  • Lucas JD, O’Doherty MJ, Wong JC, Bingham JB, McKee PH, Fletcher CD et al. (1998) Evaluation of fluorodeoxyglucose positron emission tomography in the management of soft-tissue sarcomas. J Bone Joint Surg Br 80(3): 441–447

    Article  PubMed  CAS  Google Scholar 

  • McCormack P, Burt M, Bains M, Martini N, Rusch VW, Ginsberg R (1992) Lung resection for colorectal metastases. Arch Surg 127: 1403–1406

    PubMed  CAS  Google Scholar 

  • Milne EN (1976) Pulmonary metastases: vascular supply and diagnosis. Int J Radiat Oncol Biol Phys 1 (7–8): 739–742

    PubMed  CAS  Google Scholar 

  • Mineo TC, Ambrogi V, Mineo D, Pompeo E (2001) Transxiphoid hand-assisted videothoracoscopic surgery. Ann Thorac Surg 83(6): 1978–1984

    Article  Google Scholar 

  • Mutsaerts E, Zoetmulder FA, Meijer S, Baas P, Hart AA, Rutgers EJ (2001) Outcome of thoracoscopic pulmonary metastasectomy evaluated by confirmatory thoracotomy. Ann Thorac Surg 72: 230–233

    Article  PubMed  CAS  Google Scholar 

  • Nagakura S, Shirai Y, Yamato Y, Yokoyama N, Suda T, Hatakeyama K (2001) Simultaneous detection of colorectal carcinoma liver and lung metastases does not warrant resection. J Am Coll Surg 193: 153–160

    Article  PubMed  CAS  Google Scholar 

  • Parsons AM, Detterbeck FC, Parker LA (2004) Accuracy of helical CT in the detection of pulmonary metastases: is intraoperative palpation still necessary? Ann Thorac Surg 78(6): 1910–1916

    Article  PubMed  Google Scholar 

  • Pastorino U (2002) History of the surgical management of pulmonary metastases and development of the International Registry. Semin Thorac Cardiovasc Surg 14(1): 18–28

    Article  PubMed  Google Scholar 

  • Pastorino U, Buyse M, Friedel G, Ginsberg R, Girard P, Goldstraw P et al. (1997) Long-term results of lung metastasectomy: Prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg 113: 37–49

    Article  Google Scholar 

  • Pinsky P, Freedman M, Oken M, Kvale P, Caporaso N, Gohagan J (2007) Prevalence of non-cancer-related abnormalities on low-dose spiral computer tomography versus chest radiograph in a screening population. Thorax 62(2): 190

    Article  PubMed  Google Scholar 

  • Rau B, Hunerbein M, Below C, Schlag PM (1998) Video-assisted thoracic surgery. Staging and management of thoracic tumors. Surg Endosc 12: 133–136

    Article  PubMed  CAS  Google Scholar 

  • Remy-Jardin J, Remy-Jardin M, Giraud F (1993) Pulmonary nodules: Detection with thick section spiral CT versus conventional CT. Radiology 187: 513–520

    PubMed  CAS  Google Scholar 

  • Robinson BJ, Rice TW, Strong SA, Rybicki LA, Blackstone EH (1999) Is resection of pulmonary and hepatic metastases warranted in patients with colorectal cancer? J Thorac Cardiovasc Surg 117: 66–76

    Article  PubMed  CAS  Google Scholar 

  • Rolle A, Pereszlenyi A, Koch R, Richard M, Baier B (2006) Is surgery for multiple lung metastases reasonable? A total of 328 consecutive patients with multiple-laser metastasectomies with a new 1318-nm Nd:YAG laser. J Thorac Cardiovasc Surg 131(6): 1236–1242

    Article  PubMed  Google Scholar 

  • Rosso F, Smirne C, Papalla E, Rena O, Ruffini E, Oliaro A (1998) Surgical treatment of lung metastases. Minerva Chir 54: 495–500

    Google Scholar 

  • Schirren J, Wassenberg D, Krysa S, Branscheid D, diRienzo G, Drings P et al. (1994) Metastasis surgery of the lung — Indications, results, and prognostic factors in the interdisciplinary concept. Pneumologie 48: 469–474

    PubMed  CAS  Google Scholar 

  • Schirren J, Krysa S, Bülzebruck H, Zweibarth A, Schneider P, Drings P et al. (1995) Results of surgical treatment of pulmonary metastases from soft tissue sarcomas. Recent Results Cancer Res 138: 123–138

    PubMed  CAS  Google Scholar 

  • Steinke K, Glenn D, King J, Clark W, Zhao J, Clingan P et al. (2004) Percutaneous imaging-guided radiofrequency ablation in patients with colorectal pulmonary metastases: 1-year follow-up. Ann Surg Oncol 11(2): 207–212

    Article  PubMed  Google Scholar 

  • Suh R, Reckamp K, Zeidler M, Cameron R (2005) Radiofrequency ablation in lung cancer: promising results in safety and efficacy. Oncology (Williston Park) 19 (11 Suppl 4): 12–21

    Google Scholar 

  • Vaughn C, Mychaskiw G, Sewell P (2002) Massive hemorrhage during radiofrequency ablation of a pulmonary neoplasm. Anesth Analg 94(5): 1149–1151

    Article  PubMed  Google Scholar 

  • Virgo KS, Naunheim KS, Johnson FE (2006) Preoperative workup and postoperative surveillance for patients undergoing pulmonary metastasectomy. Thorac Surg Clin 16(2): 125–131, v.

    Article  PubMed  Google Scholar 

  • Vogl TJ, Wetter A, Lindemayr S, Zangos S (2005) Treatment of unresectable lung metastases with transpulmonary chemoembolization: preliminary experience. Radiology 234(3): 917–922

    Article  PubMed  Google Scholar 

  • Watanabe M, Deguchi H, Sato M, Ozeki Y, Tanaka S, Izumi Y et al. (1998) Midterm results of thoracoscopic surgery for pulmonary metastases especially from colorectal cancers. J Laparoend & Adv Surg Techn 8: 195–200

    Article  CAS  Google Scholar 

  • Welter S, Jakobs J, Krbek T, Poettgen C, Stamatis G (2007) Prognostic impact of lymph node involvement in pulmonary metastasis from colorectal cancer. Eur J Cardiothorac Surg 31(2): 167–172

    Article  PubMed  Google Scholar 

  • Zanella A, Marchet A, Mainente P, Nitti D, Lise M (1997) Resection of pulmonary metastases from colorectal carcinoma. Eur J Surg Oncol 23: 424–427

    Article  PubMed  CAS  Google Scholar 

  • Zollinger A, Hofer CK, Pasch T (2001) Preoperative pulmonary evaluation: facts and myths. Curr Opin in Anaesthesiol 14: 59–63

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik für Chirurgie und Chirurgische Onkologie, Charité, Campus Buch, Schwanebecker Chaussee 50, 13125, Berlin, Deutschland

    Prof. Dr. B. Rau

  2. Allgemein- Thorax- und Gefäßchirurgie Universitätsklinik für Chirurgie, Medizinische Universität Wien, Allgemeines Krankenhaus, Währinger Gürtel 18-20, 1090, Wien, Österreich

    Prof. Dr. D. Kandioler (MBA)

  3. Chefarzt Thoraxchirurgie und thorakale Endoskopie, Ruhrlandklinik Essen-Heidhausen, Tüschener Weg 40, 45239, Essen, Deutschland

    Prof. Dr. G. Stamatis

Authors
  1. Prof. Dr. B. Rau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prof. Dr. D. Kandioler
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Prof. Dr. G. Stamatis
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. stv. Vorstand der Universitätsklinik für Chirurgie Wien, Medizinische Universität Wien, Universitätsklinik für Chirurgie, Wien, Österreich

    Michael Gnant

  2. Direktor des Charité Comprehensive Cancer Center, Universitätsmedizin Berlin, Berlin, Deutschland

    Peter M. Schlag

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag/Wien

About this chapter

Cite this chapter

Rau, B., Kandioler, D., Stamatis, G. (2008). Lungenmetastasen. In: Gnant, M., Schlag, P.M. (eds) Chirurgische Onkologie. Springer, Vienna. https://doi.org/10.1007/978-3-211-48613-9_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-211-48613-9_13

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-48612-2

  • Online ISBN: 978-3-211-48613-9

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation