Atherosclerotic Plaque Characterisation by Imaging

  • S. P. S. Howarth
  • J. U. King-Im
  • J. H. Gillard


Carotid artery stenosis is known to be a significant risk factor for stroke and indeed extracranial atheroma is the single most important contributor to non-haemorrhagic stroke in the developed world. Studies such as the European Carotid Surgery Trial (ECST) [63], [11] and North American Symptomatic Carotid Endarterectomy Trial (NASCET) [25], despite some methodological differences, demonstrated a significant benefit for endarterectomy in symptomatic carotid stenosis of more than 70%. More recently, evidence has been published in the form of the Asymptomatic Carotid Surgery Trial (ACST) [34], that intervention in the asymptomatic population with a stenosis of 70% or more may be of benefit providing the associated risks and likely morbidity of the intervention is low.


Carotid Stenosis Carotid Plaque Lipid Core Plaque Morphology Symptomatic Carotid 
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Copyright information

© Springer-Verlag/Wien 2007

Authors and Affiliations

  • S. P. S. Howarth
    • 1
  • J. U. King-Im
    • 1
  • J. H. Gillard
    • 1
  1. 1.University Department of Radiology and Department of NeurosurgeryAddenbrooke’s HospitalCambridgeUK

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