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Pet Imaging in Carotid Stenosis

  • C. P. Derdeyn
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Abstract

Positron Emission Tomography (PET) is a physiological, not anatomical imaging method: it is not used for the measurement or detection of carotid artery disease. It is primarily a research tool that has several important applications for the study of human carotid atherosclerotic disease. Functional imaging methods, including PET, have provided compelling data that embolic and hemodynamic factors have a synergistic effect on stroke risk. The foremost role of PET has been in studies of the assessment of the hemodynamic and metabolic effects of these lesions on the distal cerebral circulation. This information has proven prognostic value. In addition, molecular imaging applications have been described, allowing investigation of physiological aspects of the plaque itself. Finally, some radiotracers may be used to identify recent brain injury. This could help distinguish symptomatic from asymptomatic lesions, a critical distinction in carotid disease.

Keywords

Cerebral Perfusion Pressure Cerebral Blood Volume Carotid Stenosis Mean Transit Time Cereb Blood Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  • C. P. Derdeyn
    • 1
  1. 1.Mallinckrodt Institute of Radiology and The Departments of Neurology and Neurological SurgeryWashington University School of MedicineSt. LovisUSA

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