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Mechanisms of receptor-mediated transmembrane signalling

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Development of Hormone Receptors

Part of the book series: EXS 53: Experientia Supplementum ((EXS,volume 53))

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Abstract

Fundamental to the successful function of any multicellular organism is an efficient communication system that can convey information from one cell to another. Although the overall function of the cell membrane is to maintain an effective barrier between the intracellular and extracellular milieu, highly specialized membrane structures (e.g. ion channels, nutrient transporters, histocompatability determinants) can be singled out as playing particularly pivotal roles in terms of selectively transmitting information from the external to the internal cell environment (and in some cases, vice versa). Over the past decade there has been much progress in the biochemical and pharmacologic characterization of the membrane constituents that participate in the transmembrane signalling process. This chapter will deal in general with selected aspects of transmembrane signalling and will focus in particular on the plasma membrane- localized processes used by pharmacologic receptors.

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Authors and Affiliations

  1. Endocrine Research Group, Department of Pharmacology and Therapeutics, University of Calgary, Faculty of Medicine, 3330 Hospital Drive N. W., Calgary, Alberta, T2N 4N1, Canada

    M. D. Hollenberg (Faculty of Medicine)

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  1. M. D. Hollenberg
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Editors and Affiliations

  1. Semmelweis University of Medicine, Budapest, Hungary

    György Csaba

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© 1987 Birkhäuser Verlag

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Hollenberg, M.D. (1987). Mechanisms of receptor-mediated transmembrane signalling. In: Csaba, G. (eds) Development of Hormone Receptors. EXS 53: Experientia Supplementum, vol 53. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9291-9_2

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  • DOI: https://doi.org/10.1007/978-3-0348-9291-9_2

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-9982-6

  • Online ISBN: 978-3-0348-9291-9

  • eBook Packages: Springer Book Archive

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