Abstract
Atherosclerosis and its complications, including ischemic heart disease. represent the leading cause of death in the industrialized world. Accordingly, considerable resources have been expended in an effort to delineate causality and to devise effective therapeutic modalities. Several trials have demonstrated that lowering of LDL-cholesterol or an elevation of HDL-cholesterol reduces the risk of adverse cardiovascular events. Nonetheless, it is recognized that greater than 50% of the survivors of myocardial infarction have normal lipid levels, thus implicating other or additional factors in the pathogenesis of atherosclerosis.
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© 1995 Birkhäuser Verlag Basel/Switzerland
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Thomas, C.E. (1995). Nitrone spin traps as reagents for the study of oxidative modification of low density lipoproteins: Implications for atherosclerosis. In: Favier, A.E., Cadet, J., Kalyanaraman, B., Fontecave, M., Pierre, JL. (eds) Analysis of Free Radicals in Biological Systems. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9074-8_10
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DOI: https://doi.org/10.1007/978-3-0348-9074-8_10
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