Skip to main content
SpringerLink
Log in

The mammalian mitochondrial respiratory chain

  • Chapter
Bioenergetics

Part of the book series: Bioelectrochemistry: Principles and Practice ((BPP,volume 4))

  • 239 Accesses

Abstract

Approximately 90% of the ATP synthesized in the cells of animals is supplied by oxidative phosphorylation. This process takes place at the inner mitochondrial membrane. The respiratory chain builds up an electrochemical membrane potential across the inner mitochondrial membrane which is used by the F1F0 ATP sythase to synthesize ATP within the mitochondrial matrix. ATP is then exported into the cytosol; this export is also driven by the membrane potential. Hence, mitochondria are the “powerhouse of the cell”.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Y Hatefi, Annu. Rev. Biochem. 54 (1985) 1015–1069.

    Article  CAS  Google Scholar 

  2. BL Trumpower, Microbiol. Rev. 54 (1990) 101–129.

    CAS  Google Scholar 

  3. P Mitchell Nature 191 (1961) 144–148.

    Article  CAS  Google Scholar 

  4. P Mitchell J. Theor. Biol. 62 (1976) 327–367.

    Article  CAS  Google Scholar 

  5. P Mitchell in Advances in Membrane Biochemistry and Bioenergetics, CH Kim, H Tedeschi, JJ Diwan, and JC Salerno (eds.) Plenum Press, New York/London, 1988, pp. 25–52.

    Google Scholar 

  6. JE Walker Q. Rev. Biophys. 25 (1992) 253–324.

    Article  CAS  Google Scholar 

  7. T Yagi Biochim. Biophys. Acta 1141 (1993) 1–17.

    Article  CAS  Google Scholar 

  8. H Weiss, T Friedrich, G Hofhaus and D Preis Eur. J. Biochem. 197 (1991) 563–576.

    Article  CAS  Google Scholar 

  9. L Hederstedt and T Ohnishi in Molecular Mechanisms in Bioenergetics, L Ernster (ed.) Elsevier, Amsterdam, 1992, pp. 163–198.

    Chapter  Google Scholar 

  10. H Schägger, U Brandt, S Gencic and G von Jagow Methods Enzymol. 260 ( 1995) 82–96.

    Article  Google Scholar 

  11. K Leonard, P Wingfield, T Arad and H Weiss J. Mol. Biol. 149 (1981) 259–274.

    Article  CAS  Google Scholar 

  12. G von Jagow, TA Link and T Ohnishi J. Bioenerg. Biomembr. 18 (1986) 157–179.

    Article  Google Scholar 

  13. H Ding, DE Robertson, F Daldal and PL Dutton Biochemistry 31 (1992) 3144–3158.

    Article  CAS  Google Scholar 

  14. G von Jagow and TA Link Methods Enzymol. 126 (1986) 253–271.

    Article  Google Scholar 

  15. S Iwata, M Saynovits, TA Link and H Michel Structure 4 (1996) 567–579.

    Article  CAS  Google Scholar 

  16. TA Link, H Schägger and G von Jagow FEBS Lett. 204 (1986) 9–15.

    Article  CAS  Google Scholar 

  17. U Brandt, L Yu, CA Yu and BL Trumpower J. Biol. Chem. (1993) 8387–8390.

    Google Scholar 

  18. RJ Almassy and RE Dickerson Proc. Natl. Acad. Sci. USA 75. (1978) 2674–2678.

    Article  CAS  Google Scholar 

  19. K Pelletier and J Kraut Science 258 (1992) 1748–1754.

    Article  CAS  Google Scholar 

  20. M Klingenberg Angew. Chem. 75 (1963) 900–907.

    Article  CAS  Google Scholar 

  21. M Klingenberg Ann. N. Y. Acad. Sci. 456 (1985) 279–288.

    Article  CAS  Google Scholar 

  22. PC Hinkle, AM Kumar, A Resetar and DA Harris Biochemistry 30 (1991) 3576–3582.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gustav Embden Zentrum der Biologischen Chemie, Klinikum der Uni Frankfurt, Frankfurt am Main, Germany

    G. von Jagow, B. M. Geier & T. A. Link

Authors
  1. G. von Jagow
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. M. Geier
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. A. Link
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut für Physikalische Chemie, Universität Freiburg, Albertstr. 23a, D-79104, Freiburg, Germany

    Peter Gräber Ph.D. (Professor for Physical Chemistry) (Professor for Physical Chemistry)

  2. Istituto Superiore di Sanità, Rome, Italy

    Giulio Milazzo (formerly Professor) (formerly Professor)

  3. Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056, Basel, Switzerland

    Dieter Walz

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Birkhäuser Verlag Basel/Switzerland

About this chapter

Cite this chapter

von Jagow, G., Geier, B.M., Link, T.A. (1997). The mammalian mitochondrial respiratory chain. In: Gräber, P., Milazzo, G., Walz, D. (eds) Bioenergetics. Bioelectrochemistry: Principles and Practice, vol 4. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-8994-0_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-8994-0_6

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-9860-7

  • Online ISBN: 978-3-0348-8994-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation