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The Th1/Th2 cytokine balance in arthritis

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T Cells in Arthritis

Part of the book series: Progress in Inflammation Research ((PIR))

Abstract

The contribution of T cells to the pathogenesis of rheumatoid arthritis (RA) has been a matter of debate which is addressed in a number of reviews and chapters of this book 1-3. The contribution of monocytes through the production of proinflammatory cytokines has been simpler to demonstrate 4. Accordingly, Interleukin (IL)-1 and tumor necrosis factor (TNF)a have been selected as important therapeutic targets 5.

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Authors and Affiliations

  1. Departments of Immunology and Rheumatology, Clinical Immunology Unit, Hôpital Edouard Herriot, Lyon, F-69437, France

    Pierre Miossec

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  1. Pierre Miossec
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Editors and Affiliations

  1. Departments of Immunology and Rheumatology Hôpital Edouard Herriot, University Claude Bernard, Lyon Cedex 03, F-69437, France

    Pierre Miossec

  2. Division of Rheumatology, UCSD School of Medicine, 9500 Gilman Drive, San Diego, CA, 92093-0656, USA

    Gary S. Firestein

  3. Department of Rheumatology, University Hospital Nijmegen, Geert Grooteplein 8, Nijmegen, NL-6525, The Netherlands

    Wim B. van den Berg

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Miossec, P. (1998). The Th1/Th2 cytokine balance in arthritis. In: Miossec, P., Firestein, G.S., van den Berg, W.B. (eds) T Cells in Arthritis. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8823-3_5

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  • DOI: https://doi.org/10.1007/978-3-0348-8823-3_5

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