Abstract
Proton pump inhibitors (PPIs) such as omeprazole, lanzoprazole and pantoprazole are chemically characterized as substituted benzimidazoles. They are chemically relatively stable at neutral pH (t 1/2 = ∼ 24 h), whereas at acidic pH they are labile and at pH ∼ 1 the half-life is ∼ 2 min.
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© 1999 Springer Basel AG
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Carlsson, E., Havu, N. (1999). Consequences of gastric acid inhibition in animals. In: Olbe, L. (eds) Proton Pump Inhibitors. Milestones in Drug Therapy MDT. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8795-3_5
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DOI: https://doi.org/10.1007/978-3-0348-8795-3_5
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-9777-8
Online ISBN: 978-3-0348-8795-3
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