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Regulation of Eosinophil Migration

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Molecular Biology of the Lung

Part of the book series: Respiratory Pharmacology and Pharmacotherapy ((RPP))

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Abstract

Eosinophils were first recognized about 100 years ago as cells with granules that display an affinity for eosin and other acidic dyes [1]. It was soon realized that the presence of eosinophils in tissue was associated with helminthic parasite infection, allergy, asthma and certain cancers. It is now generally believed that eosinophils are important effector cells in the beneficial host defence inflammatory response against helminthic parasites, and yet they can also play a major role in the excessive and inappropriate inflammatory responses seen in allergy and asthma.

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Authors and Affiliations

  1. Leukocyte Biology, Biomedical Sciences Division, Imperial College School of Medicine, London, UK

    Peter J. Jose, Anne Burke-Gaffney & Timothy J. Williams

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  1. Peter J. Jose
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  2. Anne Burke-Gaffney
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  3. Timothy J. Williams
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Editors and Affiliations

  1. Department of Respiratory Medicine, University Hospital Birmingham, Edgbaston, Birmingham, B15 2TH, UK

    Robert A. Stockley

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Jose, P.J., Burke-Gaffney, A., Williams, T.J. (1999). Regulation of Eosinophil Migration. In: Stockley, R.A. (eds) Molecular Biology of the Lung. Respiratory Pharmacology and Pharmacotherapy. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8784-7_7

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  • DOI: https://doi.org/10.1007/978-3-0348-8784-7_7

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