Abstract
A FDG-CDET examination on a Picker gamma-camera equiped with coincidence detection and thick cristals was performed in 80 patients during the 2nd half of 1997. Sensitivity and specificity were both 100% for the detection of malignancy in primary lung tumours. Accuracy was 91% for the detection of hilar or mediastinal lymph nodes involvement vs 59% for CT; lymphangitic carcinomatosis, metastases and concomittant tumours were also successfully detected and confirmed. FDG-CDET contributed to significant management changes in 30% of the patients referred for lung abnormalities. FDG-CDET was also usefull in “occult” recurrence of colorectal cancer with an accuracy of 78% vs 42% for CT in this difficult indication; a longer follow-up is needed to be able to evaluate all the 25 patients whose management have been adequately modified in 60% of the cases. We conclude that the diagnostic performances of FDG-CDET derived from our current series cannot be distinguished from the corresponding results published with FDG-PET.
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Hustinx R, Paulus P, Rigo P, Yeung HW, Macxapinlac HA, Larson SM. In: Clinical PET in oncology. Lung tumors. GE Medical Systems Editor; 1996: 16–31.
Dewan NA, Reeb SD, Gupta NC et al. PET-FDG imaging and transthoracic needle lung aspiration biopsy in evaluation of pulmonary lesions. A comparative risk-benefit analysis. Chest 1995; 108: 441–446.
Valk PE, Pounds TR, Hopkins DM et al. Staging non-small cell lung cancer by whole body positron emission tomographic imaging. Ann Thorac. Surg. 1995; 60: 1573–82.
Wahl RL, Quint LE, Greenough RL et al. Staging of mediastinal non-small cell lung cancer with FDG PET, CT and fusion images: preliminary prospective evaluation. Radiology 1994; 191: 371–377.
Inoue T, Kim EE, Komki R et al. Detecting recurrent or residual lung cancer with FDG-PET. J Nucl Med 1995; 36: 788–793
Lewis P, Griffin S, Marsden P et al. Whole body 18F-fluorodeoxyglucose positron emission tomography in preoperative evaluation of lung cancer. Lancet 1994; 344: 1265–1266.
Hustinx R, Paulus P, Rigo P, Yeung HW, Macxapinlac HA, Larson SM. In: Clinical PET in oncology. Tumors of the gastro-intestinal tract. GE Medical Systems Editor; 1996: 32–45.
Schiepers C, Penninckx F, De Vadder N et al. Contribution of PET in the diagnosis of recurrent colorectal cancer. Eur J Surg Oncol 1995; 21: 517–522.
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© 1999 Springer Basel AG
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Grahek, D. et al. (1999). Assessment of Pulmonary Nodules and Colorectal Cancer Recurrences by FDG Scan on an «Ordinary» Coincidence Gamma Camera (CDET). In: Bergmann, H., Köhn, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research XXIII. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8782-3_30
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DOI: https://doi.org/10.1007/978-3-0348-8782-3_30
Publisher Name: Birkhäuser, Basel
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