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Comparison of Contrast Enhanced MRI, Tc-99m Hydroxy-Methylene Diphosphonate and Tc-99m Tetrofosmin Scinti-Mammography in Patients with Suspicious Breast Lesions

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Radioactive Isotopes in Clinical Medicine and Research XXIII

Abstract

In patients with suspicious breast lesions, scintimammography (SM) using Tc-99m tetrofosmin (TETRO) and hydroxymethylene-diphosphonate (HDP) and Gd-DTPA MRI were performed. For both TETRO and MRI sensitivity was 93% compared to 71% for HDP; specificity was lower for TETRO and HDP (71%) than for MRI (86%). This preliminary study shows that, in contrast to HDP, TETRO SM and Gd-DTPA MRI are of additional diagnostic value in diagnosing breast cancer.

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References

  1. Kopans DB. Positive predictive value of mammography. AJR 1992; 158:521–526.

    PubMed  CAS  Google Scholar 

  2. Heywang-Köbrunner SH. Contrast enhanced magnetic resonance imaging of the breast. Invest Radiol 1994;29:94–104

    Article  PubMed  Google Scholar 

  3. Waxman AD, Ramanna L, Memsic LD, Forster CE, Silberman AW, Gleischman SH, Brenner RJ, Brachman MB, Kuhar CJ, Yadegar J. Thallium scintigraphy in the evaluation of mass abnormalities of the breast. J Nucl Med 1993; 34:18–23

    PubMed  CAS  Google Scholar 

  4. Lind P, Smola MG, Lechner P, Ratschek M, Klima G, Költringer P, Steindorfer P, Eber O. The immunoscintigraphic use of Tc-99m labelled monoclonal antibodies (BW 431/126) in patients with suspected primary, recurrent and metastatic breast cancer. Int J Cancer 1991; 47:865–869.

    Article  PubMed  CAS  Google Scholar 

  5. Lind P, Gallowitsch HJ, Mikosch P, Kresnik E, Gomez I, Oman J, Dinges HP, Boniface G. Radioimmunoscintigraphy with Tc-99m labeled monoclonal antibody 179H.82 in suspected primary, recurrent and metastatic breast cancer. Clin Nucl Med 1997; 22:30–34

    Article  PubMed  CAS  Google Scholar 

  6. Piccolo S, Lastoria S, Mainolfi C, Muto P, Bazzicalupo L, Salvatore M. Tc-99m Methylene diphosphonate scintimammography to image primary breast cancer. J Nucl Med 1995; 36:718–724.

    PubMed  CAS  Google Scholar 

  7. Palmedo H, Grünwald F, Bender H, Schomburg A, Mallmann P, Krebs D, Biersack HJ. Scintimammography with technetium-99m methoxyisobutylisonitrile: comparison with mammography and magnetic resonance imaging. Eur J Nucl Med 1996:23:940–946.

    Article  PubMed  CAS  Google Scholar 

  8. Tiling R, Sommer H, Pechmann M, Moser R, Kress K, Pfluger T, Tatsch K, Hahn K. Comparison of technetium-99m sestamibi scintimammography with contrast enhanced MRI for diagnosis of breast cancer. J Nucl Med 1997:38:58–62.

    PubMed  CAS  Google Scholar 

  9. Mansi L, Rambaldi PF, Proccacini E, Di Gregorio F, Laprovitera A, Pecori B, Del Vecchio W. Scintimammography with technetium 99m tetrofosmin in the diagnosis of breast cancer and lymph node metastases. Eur J Nucl Med 1996;23:932–939.

    Article  PubMed  CAS  Google Scholar 

  10. Lind P, Gallowitsch HJ, Kogler D, Kresnik E, Mikosch P, Gomez I. Tc-99m tetrofosmin scintimammography: A prospective study in primary breast lesions. Nuklearmedizin 1996;35:225–229

    PubMed  CAS  Google Scholar 

  11. Arbab AS, Koizumik K, Toyama K, Arki T. Uptake of technetium-99m tetrofosmin, technetium-99m MIBI and thallium-201in tumor cell lines. J Nucl Med 1996;37:1551–1556.

    PubMed  CAS  Google Scholar 

  12. Boubaker A, Franzetti A, Pellanda A, Bischof Delaloye A. Reliability of Tc-99m Dicarboxypropane-Diphosphonate (DPD) for breast cancer imaging. J Nucl Med 1997; 38:21P

    Google Scholar 

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© 1999 Springer Basel AG

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Lind, P. et al. (1999). Comparison of Contrast Enhanced MRI, Tc-99m Hydroxy-Methylene Diphosphonate and Tc-99m Tetrofosmin Scinti-Mammography in Patients with Suspicious Breast Lesions. In: Bergmann, H., Köhn, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research XXIII. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8782-3_24

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  • DOI: https://doi.org/10.1007/978-3-0348-8782-3_24

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9772-3

  • Online ISBN: 978-3-0348-8782-3

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