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The effect of fatty acid composition and retinoic acid on human keratinocyte plasma membrane viscosity

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Fatty Acids and Inflammatory Skin Diseases

Part of the book series: Progress in Inflammation Research ((PIR))

Abstract

Lipids, specifically fatty acids and their derivatives, play important and widely varying roles in human epidermis. They are key building blocks in all membranes and in the structures forming the outer layers of skin, and they undergo an active metabolic process that provides many compounds other than the important β-oxidation product, acetyl coenzyme A (CoA). This review focuses on the metabolism of these lipids in mammalian tissues, in the skin and its epidermal component, and in human epidermal cells grown in culture (keratinocytes).

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Author information

Authors and Affiliations

  1. Department of Surgery, University of Michigan Medical School, Kresge I, R-5659, Ann Arbor, MI 48109-0592, USA

    Cynthia L. Marcelo

  2. Biophysics Research Division, University of Michigan Medical School, Ann Arbor, Ml 48109-1055, USA

    William R. Dunham

Authors
  1. Cynthia L. Marcelo
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  2. William R. Dunham
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Editor information

Editors and Affiliations

  1. Department of Dermatology, University of Kiel, Schittenhelmstr. 7, D-24105, Kiel, Germany

    Jens-Michael Schröder

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Marcelo, C.L., Dunham, W.R. (1999). The effect of fatty acid composition and retinoic acid on human keratinocyte plasma membrane viscosity. In: Schröder, JM. (eds) Fatty Acids and Inflammatory Skin Diseases. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8761-8_9

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  • DOI: https://doi.org/10.1007/978-3-0348-8761-8_9

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9762-4

  • Online ISBN: 978-3-0348-8761-8

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