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Cytokine-nerve growth factor interactions in inflammatory hyperalgesia

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Cytokines and Pain

Part of the book series: Progress in Inflammation Research ((PIR))

Abstract

Primary sensory neurons interface between the external environment and the central nervous system. To detect and transfer to the CNS information describing the stimuli that impinge upon the body, the PSN have highly specialized adaptations. These include the expression of a broad number of ion channels, receptors, neurotransmitters and neuromodulators, together with the establishment of highly ordered patterns of innervation of the peripheral target and central neurons.

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  1. Division of Endocrinology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Herts, EN6 3QG, UK

    Stephen Poole

  2. Neural Plasticity Research Group, Dept of Anesthesia, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Room 4309, Charlestown, MA, 02129, USA

    Clifford J. Woolf

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  1. Dept. of Psychology, University of Colorado at Boulder, Boulder, CO, 80309-0345, USA

    Linda R. Watkins  & Steven F. Maier  & 

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Poole, S., Woolf, C.J. (1999). Cytokine-nerve growth factor interactions in inflammatory hyperalgesia. In: Watkins, L.R., Maier, S.F. (eds) Cytokines and Pain. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8749-6_5

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