Abstract
The microinjection technique provides an alternative to molecular genetics to study the role of specific proteins that are involved in signal transduction. In this study, we microinjected macromolecular inhibitors of the inositol trisphosphate (InsP3) receptor to examine its role in the mobilization of intracellular calcium (Ca2+ i) and extracellular Ca2+ entry following activation of the plateletderived growth factor (PDGF) receptor.
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Mathias, R.S., Ives, H.E. (1999). Role of the InsP3 Receptor in Intracellular Ca2+ Release and Ca2+ Entry. In: Lacal, J.C., Feramisco, J., Perona, R. (eds) Microinjection. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8705-2_10
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DOI: https://doi.org/10.1007/978-3-0348-8705-2_10
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-7643-6019-1
Online ISBN: 978-3-0348-8705-2
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