Abstract
Solid phase synthesis has expanded dramatically since the introduction of small molecule synthesis on solid support. Polymer-supported synthesis had previously been used primarily for peptide synthesis, but has recently become an indispensable tool for preparing large numbers of compounds due to the relative ease of manipulation and amenability to automation. Although this review will focus on applications to anti-inflammatory targets, there is widespread use of solid phase synthesis towards other disease areas and a large number of compound types can be prepared using this technology [1].
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Dankwardt, S.M. (2000). Solid phase synthesis: Applications to combinatorial libraries. In: Kahn, M. (eds) High Throughput Screening for Novel Anti-Inflammatories. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8462-4_1
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DOI: https://doi.org/10.1007/978-3-0348-8462-4_1
Publisher Name: Birkhäuser, Basel
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