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Inherited deficiencies and activity variants of the mammalian carbonic anhydrases

  • Chapter
The Carbonic Anhydrases

Part of the book series: EXS 90 ((EXS,volume 90))

Abstract

The carbonic anhydrases are involved in a variety of physiological functions that are important for the survival of nearly all species. The most important biochemical function of these enzymes is the interconversion of carbon dioxide and water into bicarbonate ions and protons. These metabolites are used in a wide variety of metabolic pathways (Tashian, 1989). Some of the enzymes have other catalytic activities, although their physiological importance is not understood at this time (Verpoorte et al., 1967; Cabiscol and Levine, 1996). In humans, twelve carbonic anhydrases or carbonic anhydrase-related proteins are known to exist that belong to the alpha family of CAs (Hewett-Emmett and Tashian, 1996).

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Author information

Authors and Affiliations

  1. Departments of Microbiology and Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, 48824-1314, USA

    Patrick J. Venta

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  1. Patrick J. Venta
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Editor information

Editors and Affiliations

  1. Lake Erie College of Osteopathic Medicine, 1858 West Grandview Boulevard, Erie, PA, 16509, USA

    W. Richard Chegwidden

  2. Medical Genetics Unit, St George’s Hospital Medical School, London, SW17 0RE, UK

    Nicholas D. Carter

  3. MRC Human Biochemical Genetics Unit, Wolfson House, University College London, 4, Stephenson Way, London, NW1 2HE, UK

    Yvonne H. Edwards

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Venta, P.J. (2000). Inherited deficiencies and activity variants of the mammalian carbonic anhydrases. In: Chegwidden, W.R., Carter, N.D., Edwards, Y.H. (eds) The Carbonic Anhydrases. EXS 90, vol 90. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8446-4_19

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  • DOI: https://doi.org/10.1007/978-3-0348-8446-4_19

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9570-5

  • Online ISBN: 978-3-0348-8446-4

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