Summary
In enterobacteria thegadsystem, which includes genes encoding PLP-dependent glutamic acid decarboxylases, is required to overcome the acid stress. Herein, we provide evidence that thegadsystem is strongly induced also during anaerobic growth and suggest the possible involvement ingadtranscriptional control of two AraC-like proteins. Similarly to other decarboxylation/antiport systems, thegadsystem would confer a unique growth advantage under anaerobic conditions by generating an electrogenic potential which can be used to fuel ATP synthesis.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Mahan, M.J., Slauch, J.M. and Mekalanos, J.J. (1996). InEscherichia coliandSalmonella.Cellular and molecular biology, 2nd Ed (Neidhart F.C.ed.) pp. 2803–2815, ASM Press, Washington D.C.
De Biase, D., Tramonti, A., Bossa, F. and Visca, P. (1999) Mol.Microbiol. 32:1198–1211.
Castanie-Cornet, M., Penfound, T.A., Smith, D., Elliott, J.F. and Foster, J.W. (1999). J. Bacteriol. 181:3525–3535.
Sanders, J.W., Leenhouts, K., Burghoorn, J., Brands, J.R., Venema, G. and Kok, J. (1998) Mol. Microbiol. 27:299–310.
Bearson, S., Bearson, B. and Foster, J.W. (1997) FEMSMicrobiol. Lett. 147:173–180.
Barth, M., Marschall, C., Muffler, A., Fischer, D. and Hengge-Aronis, R. (1995) J. Bacteriol. 177:3455–3464.
Atlung, T., Sund, S., Olesen, K. and Bronsted, L.(1996)J.Bacteriol.178:3418–3425.
Watson, N., Dunyak, D.S., Rosey, E.L., Slonczewski, J.L. and Olson, E.R.(1992)JBacteriol.174:530–540.
Casadaban, M.J., Chou, J. and Cohen, S.N. 1980)J. Bacteriol.143:971–980.
De Biase, D., Tramonti, A., John, R.A. and Bossa, F.(1996) Protein. Expr. Purif. 8:430–43 8.
Miller, J.H.(1972) Experiments in Molecular Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
Auger, E.A., Redding, K.E., Plumb, T., Childs, L.C., Meng, S.Y. and Bennett, G.N (1989) Mol. Microbiol.3: 609–620.
Stim-Herndon, K.P., Flores, T.M. and Bennett, G.N.(1996) Microbiology 142: 1311–1320.
Sofia,H.J.,Burland,V.,Daniels, D.L.,Plunkett III, G. and Blattner,F.R. (1994) Nucleic Acids Res. 22:2576–2586.
Gallegos, M-T., Michan, C. and Ramos, J.L. (1993) Nucleic Acids Res. 21:807–810.
Prosseda, G., Fradiani, P.A., Di Lorenzo, M., Falconi, M., Micheli, G., Casalino, M., Nicoletti, M. and Colonna, B. (1998) Res. Microbiol. 149:15–25.
Higuchi, T., Hayashi, H. and Abe, K. (1997) J.Bacteriol. 179:3362–3364.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer Basel AG
About this paper
Cite this paper
Tramonti, A., Visca, P., Bossa, F., De Biase, D. (2000). Environmental Stimuli and Regulatory Factors Affecting the Expression of the Glutamic Acid Decarboxylase System in Escherichia coli . In: Iriarte, A., Martinez-Carrion, M., Kagan, H.M. (eds) Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8397-9_7
Download citation
DOI: https://doi.org/10.1007/978-3-0348-8397-9_7
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-9549-1
Online ISBN: 978-3-0348-8397-9
eBook Packages: Springer Book Archive