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Inhibition of neurogenic inflammation in preventive migraine treatment

  • Margarita Sánchez del Río
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Part of the Progress in Inflammation Research book series (PIR)

Abstract

Preventive pharmacological treatment of migraine aims at reducing the frequency, intensity and duration of the attacks by intervening, at the earliest stage possible, in migraine pathogenesis. The medications effective in migraine prevention conceivably act at multiple sites to raise the threshold for spreading cortical depression, to inhibit the mechanisms of vasodilation or neurogenic inflammation, or to enhance central anti-nociception. They most likely work through more than one mode of action and this review will focus on the evidence for an action in inhibiting neurogenic inflammation.

Keywords

Ergot Alkaloid Neurogenic Inflammation Migraine Prophylaxis Trigeminal Nucleus Caudalis Carotid Blood Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Basel AG 2002

Authors and Affiliations

  • Margarita Sánchez del Río
    • 1
  1. 1.Headache Unit, Department of NeurologyFundación Hospital Alcorcón, Juan Carlos I UniversityMadridSpain

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