Summary
In recent years a number of different individual-based models for spatiotemporal dynamics in multicellular organisms or parts of them have been established. Individual-based models (here: individuum = cell) become necessary if (i) one is interested in understanding the organization principles in tissues down to length scales of the order of a cell diameter in order to link the microscopic dynamics with a collective phenomenon, and (ii) the phenomenon under study includes variations of material or kinetic properties on length scales of the order of the cell diameter. In this article we give a brief overview over a number of individual-based model approaches.
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Drasdo, D. (2003). On Selected Individual-based Approaches to the Dynamics in Multicellular Systems. In: Alt, W., Chaplain, M., Griebel, M., Lenz, J. (eds) Polymer and Cell Dynamics. Mathematics and Biosciences in Interaction. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8043-5_15
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