Skip to main content

Treatment and prevention of antibiotic-associated colitis

  • Chapter
Pharmacotherapy of Gastrointestinal Inflammation

Part of the book series: Progress in Inflammation Research ((PIR))

Abstract

Diarrhoea is a relatively frequent side effect seen during treatments with various drugs and about 700 drugs have been implicated in diverse forms of colitis [1, 2]; among the drugs the most frequently involved in diarrhoea, antibiotics account for the predominant therapeutic agents responsible for intestinal disorders.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Chassany O, Michaux A, Bergmann JF (2000) Drug-induced diarrhoea.Drug Safety22:52–72

    Article  Google Scholar 

  2. Blomberg B, Järnerot G (2000) Clinical evaluation and management of acute severe col-itis.Inflamm Bowel Dis6: 214–227

    Article  PubMed  CAS  Google Scholar 

  3. Högenauer C, Hammer HF, Krejs GJ, Reisinger EC (1998) Mechanisms and management of antibiotic-associated diarrheoa.Clin Infect Dis27: 702–710

    Article  PubMed  Google Scholar 

  4. McFarland LV, Surawicz CM, Rubin M, Fekety R, Elmer GW, Greenberg RN (1999) RecurrentClostridium difficiledisease: Epidemiology and clinical characteristics.Infect Control Hosp Epidemiol20: 43–50

    Article  Google Scholar 

  5. Wiström J, Norrby SR, Myhre EB, Eriksson S, Granström G, Lalergren L, Englund G, Nord CE, Svenungsson B (2001) Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: A prospective study.J Antimicrob Chemother47: 43–50

    Article  PubMed  Google Scholar 

  6. Carbon C, Richard A, Bons B (1994) Les colites pseudomembraneuses associées à l’an-tibiothérapie.Therapie49: 325–331

    PubMed  CAS  Google Scholar 

  7. Piche T, Rampal P (2002) Colites infectieuses de l’adulte: Prise en charge diagnostique et thérapeutique.Antibiotiques4: 11–17

    Google Scholar 

  8. Bartlett JG (1995) Antibiotic-associated diarrhoea. In: MJ Blaser, PD Smith, JI Ravdin, HB Greenberg, RL Guerrant (eds):Infections of the gastrointestinal tract.Raven Press Ltd, New York, 893–904

    Google Scholar 

  9. Bartlett JG, Moon N, Chang TW, Taylor N, Onderdonk AB (1978) Role ofClostridium difficilein antibiotic-associated pseudo-membranous colitis.Gastroenterology75: 778–782

    PubMed  CAS  Google Scholar 

  10. Zimmerman MJ, Bak A, Sutherland LR (1997) Review article: Treatment ofClostridium difficileinfection.Aliment Pharmacol Ther 11:1003–1012

    Article  PubMed  CAS  Google Scholar 

  11. Surawicz CM, McFarland LV (1997) Pseudomembranous colitis: Causes and cures.Digestion60: 91–100

    Article  Google Scholar 

  12. Gabaron-Kerleguer A, Soler CP, Désidéri-Vaillant C, Garrabé E, Cavallo JD (2001) Diarrhées post-antibiothérapie.Med Mal Infect31: 650–655

    Article  Google Scholar 

  13. Bernasconi P (1984)Flore et écosytème intestinal.Editions scientifiques des laboratoires biocodex, Paris.

    Google Scholar 

  14. Tancrède C (1992) Role of human microflora in health and disease.Eur J Clin Microbiol Infect Dis 11:1012–1015

    Article  PubMed  Google Scholar 

  15. Weber FH, Richards RD, Mc Callum RW (1993) Erythromycin: A motilin agonist and gastrointestinal prokinetic agent. AmJ Gastroenterol8: 485–490

    Google Scholar 

  16. Rubin MS, Bodenstein LE, Kent KC (1995) SevereClostridium difficilecolitis.Dis Colon Rectum38: 350–354

    Article  PubMed  CAS  Google Scholar 

  17. Bergogne-Bérézin E (2000) Treatment and prevention of antibiotic-associated diarrhoea.Intern J Antimicrob Agents16: 521–526

    Article  Google Scholar 

  18. Bouhnik Y, Marteau Ph, Rambaud JC (1993) Utilisation des probiotiques chez l’homme.Ann Gastroentérol Hépatol29: 241–249

    CAS  Google Scholar 

  19. Elmer GW, Surawicz CM, McFarland LV (1996) Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections.JAMA275: 870–876

    Article  PubMed  CAS  Google Scholar 

  20. Periti P, Tonelli F (2001) Preclinical and clinical pharmacology of biotherapeutic agents:Saccharomyces boulardii. J Chemother13: 473–493

    CAS  Google Scholar 

  21. Kitasawa H, Ino T, Kawai Y, Itoh T, Saito T (2002) A novel immunostimulating aspect ofLactobacillus gasseriinduction of “gasserokin” as chemo-attractants for macrophages.Int J Food Microbiol 77: 29–38

    Article  Google Scholar 

  22. Siitonen S, Vapaatalo H, Salminen S et al (1990) Effect ofLactobacillusGG yoghurt in prevention of antibiotic-associated diarrhoea.Ann Med22: 57–59

    Article  PubMed  CAS  Google Scholar 

  23. Buts JP, Corthier G, Delmee M (1993)Saccharomyces boulardiiforClostridium diffi-cile-associated enteropathies in infants.J Pediatr Gastroenterol Nutr16: 419–425

    Article  PubMed  CAS  Google Scholar 

  24. Tankanow RM, Ross MB, Ertel IJ, Dickinson DG, McCormick LS, Garfinkel JF (1990) A double-blind, placebo-controlled study of the efficacy of lactinex in the prophylaxis of amoxicillin-induced diarrhoea.Drug Intelligence Clinical Pharmacy24: 382–384

    CAS  Google Scholar 

  25. Colombel JF, Cortot A, Neut C, Romond C (1987) Yoghurt withBi fidobacterium longumreduces erythromycin-induced gastrointestinal effects.Lancet2: 43

    Article  PubMed  CAS  Google Scholar 

  26. Young RJ, Whitney DB, Hanner TL, Antonson DL, Lupo JV, Vanderhoof JA (1998) Prevention of antibiotic-associated diarrhoea utilizingLactobacillusGG.Gastroenterology114: A435

    Article  Google Scholar 

  27. Adam, Barret, Barret-Bellet et al (1977) Essais cliniques contrôlés en double insu de l’Ultra-Levure lyophilisée. Etude multicentrique par 25 médecins de 388 cas. Gazette Med France 84: 2072–2078

    Google Scholar 

  28. Surawicz CM, Elmer GW, Speelman P, McFarland LV, Chinn J, Van Belle G (1989) Prevention of antibiotic-associated diarrhoea bySaccharomyces boulardii:A prospective study.Gastroenterology96: 981–988

    PubMed  CAS  Google Scholar 

  29. McFarland LV, Surawicz CM, Greenberg RN et al (1995) Prevention of ß-lactam-associated diarrhoea bySaccharomyces boulardiicompared with placebo. AmJ Gastroenterology90: 439–448

    CAS  Google Scholar 

  30. Bergogne-Bérézin E. (1995) Impact écologique de l’antibiothérapie. Place des microorganismes de substitution dans le contrôle des diarrhées et colites associées aux antibiotiques.Presse Med24: 145–156

    PubMed  Google Scholar 

  31. Gorbach SL, Chang TW, Goldin B (1987) Successful treatment of relapsingClostridium difficilecolitis with Lactobacillus GG.Lancet2: 1519

    Article  PubMed  CAS  Google Scholar 

  32. Biller JA, Katz AJ, Flores AF, Buie TM, Gorbach SL (1995) Treatment of recurrentClostridium difficilecolitis withLactobacillusGG.J Pediatr Gastroenterol Nutr21: 224–226

    Article  PubMed  CAS  Google Scholar 

  33. McFarland LV, Surawicz CM, Greenberg RN et al (1994) Essai clinique randomisé, à double insu contre placebo, deSaccharomyces boulardiien association à une antibiothérapie standard dans le traitement de l’infection à Clostridium difficile. DAMA271: 1913–1918

    Article  Google Scholar 

  34. Castagliuolo I, Riegler MF, Valenick L, LaMont JT, Pothoulakis C (1999)Saccharomyces boulardiiprotease inhibits the effects ofClostridium difficiletoxins A and B in human colonic mucosa.Infect Immun67: 302–307

    PubMed  CAS  Google Scholar 

  35. Hamilton-Miller JMT (1997) Living in the “post-antibiotic era”: could the use of probiotics be an effective strategy?Clin Microbiol Inf3: 2–4

    Article  Google Scholar 

  36. Plein J, Hotz J (1993) Therapeutic effect ofSaccharomyces boulardiion mild residual symptoms in a stable phase of Crohn’s disease with respect to chronic diarrhoea, a pilot study.Gastroenterol31: 129–134

    CAS  Google Scholar 

  37. Armuzzi A, Cremonini F, Ojetti V et al (2001) Effect ofLactobacillusGG supplementation on antibiotic-associated gastrointestinal side effects duringHelicobacter pylorieradication therapy: A pilot study.Digestion63: 1–7

    Article  PubMed  CAS  Google Scholar 

  38. Marteau P, Cellier C (1999) Immunological effects of biotherapeutic agents. In: GW Elmer, L Mc Farland, C Surawicz (eds):Biotherapeutic agents and infectious diseases.Human Press Inc, Towota NJ, 121–144

    Chapter  Google Scholar 

  39. Sobel JD (1999) Biotherapeutic agents as therapy for vaginitis. In GW Elmer, L Mc Far-land, C Surawicz (eds):Biotherapeutic agents and infectious diseases.Human Press Inc, Towota NJ, 221–244

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Springer Basel AG

About this chapter

Cite this chapter

Bergogne-Bérézin, E. (2004). Treatment and prevention of antibiotic-associated colitis. In: Guglietta, A. (eds) Pharmacotherapy of Gastrointestinal Inflammation. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7930-9_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7930-9_4

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9625-2

  • Online ISBN: 978-3-0348-7930-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics