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The role of bone morphogenetic proteins in developing and adult kidney

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Bone Morphogenetic Proteins: Regeneration of Bone and Beyond

Part of the book series: Progress in Inflammation Research ((PIR))

Abstract

The kidney has been identified as a major site of BMP-7 (BMP-7) synthesis during embryonal and postnatal development [1-4]. Gene knockout [5, 6] and in vitro experiments [4, 7] demonstrated the importance of BMP-7 in kidney development. Many developmental features are recapitulated during renal injury, and BMPs may be important in both preservation of function and resistance to injury [8, 9]. BMP7 has a cytoprotective and anti-inflammatory effect in both acute and chronic renal failure [8, 9].

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Authors and Affiliations

  1. Department of Anatomy, School of Medicine, University of Zagreb, Salata 11, Zagreb, 10 000, Croatia

    Fran Borovecki, Petra Simic, Lovorka Grgurevic & Slobodan Vukicevic

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  1. Fran Borovecki
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  2. Petra Simic
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  3. Lovorka Grgurevic
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  4. Slobodan Vukicevic
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  1. Laboratory for Mineralized Tissues, School of Medicine, Salata 11, Zagreb, HR, 10000, Croatia

    Slobodan Vukicevic

  2. Genzyme Corporation, One Mountain Road, Framingham, MA, 01701-9322, USA

    Kuber T. Sampath

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Borovecki, F., Simic, P., Grgurevic, L., Vukicevic, S. (2004). The role of bone morphogenetic proteins in developing and adult kidney. In: Vukicevic, S., Sampath, K.T. (eds) Bone Morphogenetic Proteins: Regeneration of Bone and Beyond. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7857-9_10

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  • DOI: https://doi.org/10.1007/978-3-0348-7857-9_10

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9598-9

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