Abstract
The welfare of animals used in biomedical research is a matter of importance to those who utilize the animals, as well as the general public. This is evidenced by the numerous laws and regulations currently governing the use of animals in effect, reflect this concern [1]. The purpose of this chapter is to provide a brief overview of these laws and regulations as they pertain to the use of animals in pharmaceutical and academic research. As most of the regulations affect animal care practices and as such are the responsibility of those who care for the animals (i.e. the attending veterinarian and the institution animal care and use committee), details for care practices will not be provided. We will, however, attempt to cover some of the responsibilities of the principal investigator who does animal based research. In addition, since these regulations are subject to change, we have tried to indicate sources where the most recent information additional sources sources and up to dated information can be obtained.
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References
McPherson CW (1984) Laws, regulations and policies affecting the use of laboratory animals. In: JG Fox, JB Cohen, FM Loew (eds): Laboratory animal medicine. Academic Press, New York, 21–30
Animal Welfare Act (Title 7 U.S.C. 2131–2156), as amended by P.L. 99–198, December 23, 1986
US Department of Health and Human Services, National Institutes of Health, Office for Protection from Research Risks. Public health service policy on human care and use of laboratory animals, revised September, 1986, pursuant to Health Research Extension Act of 1985 (P.L. 99–158, November 20, 1985 )
US Department of Health and Human Services, Food and Drug Administration (1994) Good laboratory practice regulations: nonclinical laboratory studies (21 CFR Part 58)
National Association for Biomedical Research (1991) State laws concerning the use -o of animals in research
Murphy RA, Rowan AN, Smeby R (eds) (1991) Annotated bibliography on laboratory animal welfare. Scientists Center for Animal Welfare, Greenbelt, MD
National Research Council, Institute of Laboratory Animal Resources (1996) Guide for the care and use of laboratory animals. National Academy Press, Washington, DC
Foundation for Biomedical Research (1987) The biomedical investigator’s handbook: for researchers using animal models. Washington, DC
Animal Welfare Institute (1985) Animals and their legal rights. Washington, DC
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© 1999 Springer Basel AG
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Litwak, K.N., Hughes, H.C. (1999). Guidelines and regulations in animal experimentation. In: Morgan, D.W., Marshall, L.A. (eds) In Vivo Models of Inflammation. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7775-6_14
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DOI: https://doi.org/10.1007/978-3-0348-7775-6_14
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-7777-0
Online ISBN: 978-3-0348-7775-6
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